Gene Symbol | USP6NL |
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Entrez Gene | 9712 |
Alt Symbol | RNTRE, TRE2NL, USP6NL-IT1 |
Species | Human |
Gene Type | protein-coding |
Description | USP6 N-terminal like |
Other Description | USP6 N-terminal-like protein|related to the N-terminus of tre |
Swissprots | A8KA79 Q5VV10 Q7L0K9 Q15400 Q92738 |
Accessions | EAW86344 Q92738 AA741061 AB449916 BAH16659 AK091487 AK292944 BAF85633 AK311094 AK311453 AM392670 CAL37548 AM393098 CAL37976 AM393366 CAL38244 AM393656 CAL38532 BC010351 AAH10351 BC042943 AAH42943 CF121539 D13644 BAA02807 DB457665 HY012494 XM_006717542 XP_006717605 XM_011519762 XP_011518064 XM_011519763 XP_011518065 XM_011519764 XP_011518066 NM_001080491 NP_001073960 NM_014688 NP_055503 NR_125732 |
Function | Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex. {ECO:0000269|PubMed:11099046, ECO:0000269|PubMed:17562788, ECO:0000269|PubMed:17684057}. |
Subcellular Location | Golgi apparatus. Cytoplasmic vesicle. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:8700515}. |
Anti-USP6NL antibody - ab127552 from Abcam
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Anti-USP6NL antibody - ab110977 from Abcam
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Anti-USP6NL antibody - ab99946 from Abcam
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Anti-USP6NL Antibody (aa451-500) - LS-C120459 from LifeSpan Bioscience
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Anti-USP6NL Antibody (aa350-400) - LS-C289508 from LifeSpan Bioscience
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Anti-USP6NL Antibody (N-Terminus) - LS-C155628 from LifeSpan Bioscience
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USP6NL Antibody - NBP1-83061 from Novus Biologicals
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USP6NL Antibody - NBP1-47264 from Novus Biologicals
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USP6NL Antibody - NBP2-20839 from Novus Biologicals
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Anti-USP6NL antibody produced in rabbit - HPA039196 from Sigma-Aldrich
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Anti-USP6NL (N-terminal) antibody produced in rabbit - SAB2700662 from Sigma-Aldrich
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USP6NL Antibody (OAAF04433) - OAAF04433 from Aviva Systems Biology
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USP6NL Antibody - abx014992 from Abbexa
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Anti-RN-tre antibody - STJ95523 from St John's Laboratory Ltd
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USP6NL antibody - 13896-1-AP from Proteintech Group
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USP6NL Polyclonal Antibody - PA003686-C19466 from Syd Labs
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USP6NL Antibody - 35136 from Signalway Antibody
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USP6NL Antibody - E11-19466C from Enogene
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USP6NL Antibody - C19466 from Assay Biotechnology
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RN-tre Antibody - A302-794A from Bethyl Labs
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Monoclonal Antibody to USP6 N-Terminal Like Protein (USP6NL) - MAL872Hu21 from Uscn Life Science Inc.
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Polyclonal Antibody to USP6 N-Terminal Like Protein (USP6NL) - PAL872Hu01 from Uscn Life Science Inc.
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Anti-USP6NL monoclonal antibody - DCABH-17363 from Creative Diagnostics
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Anti-USP6NL (aa 1-164) polyclonal antibody - DPABH-23204 from Creative Diagnostics
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USP6NL Polyclonal Antibody - PA5-31749 from Thermo Fisher Scientific
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