Gene Symbol | COL17A1 |
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Entrez Gene | 1308 |
Alt Symbol | BA16H23.2, BP180, BPA-2, BPAG2, LAD-1 |
Species | Human |
Gene Type | protein-coding |
Description | collagen, type XVII, alpha 1 |
Other Description | 180 kDa bullous pemphigoid antigen 2|alpha 1 type XVII collagen|bA16H23.2 (collagen, type XVII, alpha 1 (BP180))|bullous pemphigoid antigen 2 (180kD)|collagen XVII, alpha-1 polypeptide|collagen alpha-1(XVII) chain|type XVII collagen alpha-1 |
Swissprots | Q9NQK9 Q9UC14 Q9UMD9 Q99018 Q5JV36 Q02802 |
Accessions | AAB51499 EAW49612 EAW49613 EAW49614 Q9UMD9 AB900157 BAO31681 AF136185 AF136186 AK309940 AU076442 BC004478 AAH04478 BC168368 AAI68368 D63465 M63730 AAA51839 M91669 AAA35605 NM_000494 NP_000485 NM_130778 |
Function | May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. |
Subcellular Location | 97 kDa linear IgA disease antigen: Secreted, extracellular space, extracellular matrix, basement membrane. Note=Localized in the lamina lucida beneath the hemidesmosomes. |
Tissue Specificity | Stratified squamous epithelia. Found in hemidesmosomes. Expressed in cornea, oral mucosa, esophagus, intestine, kidney collecting ducts, ureter, bladder, urethra and thymus but is absent in lung, blood vessels, skeletal muscle and nerves. {ECO:0000269|PubMed:1748679, ECO:0000269|PubMed:8618013}. |
Top Pathways | Protein digestion and absorption |
COL17A1 / Collagen XVII Antibody Blocking Peptide - LS-E9940 from LifeSpan Bioscience
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COL17A1-Antibody-Center-Blocking-Peptide - BP9099c from Abgent, a WuXi AppTec company
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Human Collagen alpha-1(XVII) chain protein - orb245702 from Biorbyt
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Human Collagen Type XVII Protein - abx066023 from Abbexa
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Collagen Type XVII (COL17), Human - 20-8383 from ARP American Research Products
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Recombinant Collagen Type XVII (COL17) - RPC135Hu01 from Uscn Life Science Inc.
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Recombinant Collagen Type XVII (COL17) - RPC135Hu01 from Cloud-clone
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Recombinant human Collagen alpha-1(XVII) chain protein - CSB-EP180994h(c) CSB-BP180994h(c) CSB-MP180994h(c) from Cusabio
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Recombinant Human Collagen alpha-1(XVII) chain(COL17A1),partial - CSB-RP180994h(c) from Cusabio
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Recombinant Human Collagen alpha-1(XVII) chain(COL17A1) ,partial - CSB-YP891970HU CSB-EP891970HU CSB-BP891970HU CSB-MP891970HU from Cusabio
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Collagen XVII Protein - NBP1-91800PEP from Novus Biologicals
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Collagen XVII Recombinant Protein Antigen - NBP2-38686PEP from Novus Biologicals
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COL17A1 Peptide, Human - M34GP03440H from Creative Peptides
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Collagen 17 alpha 1 Blocking Peptide - CBP7515 from Cohesion Biosciences
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COL17A1 peptide - orb13071 from Biorbyt
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COL17A1 Recombinant Protein (OPCD02312) - OPCD02312 from Aviva Systems Biology
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Recombinant human Collagen alpha-1(XVII) chain protein - AP72374 from Signalway Antibody
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Collagen alpha-1 (XVII) chain, Recombinant Protein - MBS9422124 from MyBioSource
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Collagen alpha-1(XVII) chain, Recombinant Protein - MBS1265558 from MyBioSource
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Collagen Type XVII (COL17), Recombinant Protein - MBS2012222 from MyBioSource
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COL17A1 peptide - orb382420 from Biorbyt
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