CHST12

Gene Symbol CHST12
Entrez Gene 55501
Alt Symbol C4S-2, C4ST-2, C4ST2
Species Human
Gene Type protein-coding
Description carbohydrate (chondroitin 4) sulfotransferase 12
Other Description carbohydrate sulfotransferase 12|chondroitin 4-O-sulfotransferase 2|chondroitin 4-sulfotransferase 2|sulfotransferase Hlo
Swissprots Q9NXY7 Q9NRB3 A4D1Z9 Q502W3
Accessions EAL23955 EAW87243 EAW87244 EAW87245 Q9NRB3 AF239822 AAF81692 AJ289131 CAB92133 AK223191 BAD96911 AK223211 BAD96931 AK313484 BAG36268 AY358574 AAQ88937 BC002918 AAH02918 BC015954 BC095492 AAH95492 DA078292 DA704587 DQ892969 ABM83895 DQ896217 ABM87216 XM_011515443 XP_011513745 XM_011515444 XP_011513746 NM_001243794 NP_001230723 NM_001243795 NP_001230724 NM_018641 NP_061111
Function Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Activity toward partially desulfated dermatan sulfate is however lower. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Widely expressed. Expressed a high level in spinal chord, heart, spleen, thyroid, pituitary gland, adrenal gland, peripheral blood leukocytes, thymus, lung, small intestine, fetal kidney, fetal spleen and fetal lung. {ECO:0000269|PubMed:10781601}.
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

Human CHST12 full length protein - ab163098 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163098 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human CHST12 full length protein - ab163099 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163099 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human CHST12 protein fragment - ab163100 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163100 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human CHST12 protein fragment - ab163101 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163101 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Human CHST12 Protein - H00055501-P02 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human CHST12 Protein - H00055501-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human CHST12 Protein - H00055501-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human CHST12 Protein - H00055501-Q02 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

CHST12 - H00055501-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

CHST12 - H00055501-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

CHST12 - H00055501-P02 from Acris Antibodies

Category Protein
Prices $370.00
Sizes 10 µg
Species Human

CHST12 - H00055501-P02-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

CHST12 - H00055501-P02-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

CHST12 - H00055501-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

CHST12 - H00055501-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

CHST12 - H00055501-Q02 from Acris Antibodies

Category Protein
Prices $370.00
Sizes 10 µg
Species Human

CHST12 - H00055501-Q02-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

CHST12 - H00055501-Q02-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

CHST12 fusion protein - Ag7648 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

CHST12 fusion protein - ag7544 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human CHST12, His-tagged - CHST12-11225H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Carbohydrate sulfotransferase 12(CHST12) - CSB-YP882084HU CSB-EP882084HU CSB-BP882084HU CSB-MP882084HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

CHST12 - TP302514 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
CHST12

Carbohydrate sulfotransferase 12 (CHST12), Recombinant Protein - MBS1320851 from MyBioSource

Category Protein
Prices $1,190.00, $1,190.00, $1,410.00, $1,410.00, $1,915.00, $1,915.00, $2,380.00, $2,380.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

CHST12 Protein - NBP1-91784PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human
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