VAPB

Gene Symbol VAPB
Entrez Gene 9217
Alt Symbol ALS8, VAMP-B, VAP-B
Species Human
Gene Type protein-coding
Description VAMP (vesicle-associated membrane protein)-associated protein B and C
Other Description VAMP-associated 33 kDa protein|vesicle-associated membrane protein-associated protein B/C
Swissprots O95292 A2A2F2 Q9P0H0 O95293
Accessions EAW75493 EAW75494 EAW75495 O95292 AB209665 BAD92902 AF086628 AAD13577 AF086629 AAD13578 AF160212 AAF67013 AK023241 BAG51174 AK024771 AK025720 AK123388 AK123538 BAG53909 AK124571 AK127252 BAC86901 AK128422 BAC87433 AK298036 BAG60336 AL833440 AY358464 AAQ88829 BC001712 AAH01712 BM968517 BT009811 AAP88813 DA450527 HQ447372 ADQ31858 NM_001195677 NP_001182606 NM_004738 NP_004729 NR_036633
Function Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation. {ECO:0000269|PubMed:16891305, ECO:0000269|PubMed:20940299, ECO:0000269|PubMed:22131369}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Note=Present in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane. {ECO:0000269|PubMed:22131369}.
Tissue Specificity Ubiquitous. Isoform 1 predominates.

VAP-B/C (H-40) - sc-98892 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
VAP-B/C (H-40): sc-98892. Western blot analysis of VAP-B/C expression in mouse kidney (A) and mouse liver (B) tissue extracts.

VAP-B/C (M-47) - sc-98891 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
VAP-B/C (M-47): sc-98891. Western blot analysis of VAP-B/C expression in non-transfected 293T: sc-117752 (A), mouse VAP-B/C transfected 293T: sc-127757 (B) and NIH/3T3 (D) whole cell lysates and mouse brain (C) and mouse liver (E) tissue extracts.

VAP-B/C (K-16) - sc-48702 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VAP-B/C (K-16): sc-48702. Western blot analysis of VAP-B/C expression in mouse brain (A) and mouse liver (B) tissue extracts.

VAP-B/C (N-12) - sc-48703 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-VAPB antibody - ab196487 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-VAPB antibody (ab196487) at 1/500 dilutionLane 1 : BT474 cell extractLane 2 : SW480 cell extractLane 3 : HepG2 cell extractLane 4 : H460 cell extractLane 5 : Raji cell extractLane 6 : Mouse brain tissue extractLane 7 : Mouse intestine tissue extract

Anti-VAPB antibody - ab103638 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-VAPB antibody (ab103638) at 1/500 dilution + Mouse lung tissue lysate at 50 µg

Anti-VAPB antibody - ab103639 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-VAPB antibody (ab103639) at 1 µg/ml + Mouse kidney tissue lysate at 50 µg

Anti-VAPB antibody - ab67062 from Abcam

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-VAPB antibody (ab67062) at 1/500 dilution + Human liver lysate at 25 µgSecondaryGoat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

Anti-VAPB antibody - C-terminal - ab139148 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-VAPB antibody - C-terminal (ab139148) at 1/100 dilution + A549 cell line lysates at 35 µgdeveloped using the ECL technique

Anti-VAPB Antibody - LS-C91904 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-VAPB Antibody (aa2-132) - LS-C126459 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-VAPB Antibody (aa50-100) - LS-C95245 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-VAPB Antibody (aa2-132, clone 12K193) - LS-C182968 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 12K193

Anti-VAPB Antibody (aa171-200, AP) - LS-C218401 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VAPB Antibody (aa171-200, APC) - LS-C218402 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VAPB Antibody (aa171-200, Biotin) - LS-C218403 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VAPB Antibody (aa171-200, FITC) - LS-C218404 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VAPB Antibody (aa171-200, Azide-free, HRP) - LS-C218405 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VAPB Antibody (aa171-200, PE) - LS-C218406 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VAPB Antibody (aa170-200) - LS-C326248 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VAPB Antibody - LS-C341593 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-VAPB Antibody (aa171-200) - LS-C157340 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
VAPB Antibody western blot of A549 cell line lysates (35 ug/lane). The VAPB antibody detected the VAPB protein (arrow).

Anti-VAPB Antibody (aa100-150) - LS-C289605 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human VAPB by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-VAPB used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Anti-VAPB Antibody (aa126-139) - LS-C344259 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from HeLa, HepG2, Jurkat, SH-SY5Y, mouse NIH/3T3 cell line and rat heart tissue lysate (from left to right) with VAPB Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.

Anti-VAPB Antibody - LS-C334013 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human liver cancer using VAPB antibody at dilution of 1:200 (x400 lens).
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