GNAL

Gene Symbol GNAL
Entrez Gene 2774
Alt Symbol DYT25
Species Human
Gene Type protein-coding
Description guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
Other Description adenylate cyclase-stimulating G alpha protein, olfactory type|guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide, olfactory type|guanine nucleotide-binding protein G(olf) subunit alpha
Swissprots Q86XU3 B7ZA26 P38405
Accessions AAD00085 CAF32888 EAX01573 EAX01574 P38405 AF493893 AAM12607 AK090868 BAC03535 AK290054 BAF82743 AK295088 BAG58129 AK307260 AK313902 BAG36625 AK316141 BAH14512 BC050021 AAH50021 BP230966 BU163496 BX097239 CB241142 DA190390 DB475200 DC323877 DC336037 HQ448004 ADQ32485 L10665 AAC37535 XM_006722323 XP_006722386 XM_006722324 XP_006722387 XM_011525654 XP_011523956 NM_001142339 NP_001135811 NM_001261443 NP_001248372 NM_001261444 NP_001248373 NM_182978 NP_892023 NM_002071
Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.
Tissue Specificity Detected in olfactory neuroepithelium, brain, testis, and to a lower extent in retina, lung alveoli, spleen. Trace amounts where seen in kidney, adrenal gland and liver. Found to be expressed in all the insulinomas examined.
Top Pathways Olfactory transduction, Calcium signaling pathway, Chagas disease (American trypanosomiasis), Amoebiasis, Dopaminergic synapse

G α s/olf (G-10) - sc-365855 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
G<sub>α s/olf</sub> (G-10): sc-365855. Western blot analysis of G<sub>α s/olf</sub> expression in TT (A) and SK-N-MC (B) whole cell lysates.

G α olf (K-14) - sc-26764 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

G α s/olf (C-10) - sc-377435 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
G<sub>α s/olf</sub> (C-10): sc-377435. Western blot analysis of G<sub>α s/olf</sub> expression in TT (A) and SK-N-MC (B) whole cell lysates.

G α olf (P-15) - sc-26763 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

G α s/olf (A-5) - sc-55545 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
G<sub>α s/olf</sub> (A-5): sc-55545. Immuno?fluorescence staining of methanol-fixed HeLa cells showing cytoplasmic and membrane local?ization.

G α s/olf (C-18) - sc-383 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Gα s/olf (C-18): sc-383. Western blot analysis of Gα s/olf expression in TT whole cell lysate.

G α s/olf (E-7) - sc-55546 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
G<sub>α s/olf</sub> (E-7): sc-55546. Immuno?fluorescence staining of methanol-fixed HeLa cells showing membrane and cytoplasmic local?ization.

G α s/olf (H-300) - sc-28585 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
G<sub>α s/olf</sub> (H-300): sc-28585. Western blot analysis of G<sub>α s/olf</sub> expression in MCF7 whole cell lysate.

Anti-GNAL antibody - ab74049 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GNAL antibody (ab74049) at 1/500 dilutionLane 1 : extracts from LOVO cellsLane 2 : extracts from LOVO cells with immunizing peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-GNAL antibody - ab91589 from Abcam

Prices $304.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GNAL antibody (ab91589) at 1/100 dilution + K562 cell line lysate at 35 µg

Anti-GNAL antibody - C-terminal - ab199379 from Abcam

Prices $382.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-GNAL antibody - C-terminal (ab199379) at 1/500 dilution + Jurkat cell lysate at 50 µgdeveloped using the ECL technique

Anti-GNAL Antibody - LS-C307707 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GNAL Antibody (aa362-411) - LS-C81894 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-GNAL Antibody (aa41-90) - LS-C120030 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from LOVO cells, using GNAL Antibody. The lane on the right is treated with the synthesized peptide.

Anti-GNAL Antibody (aa50-100) IHC-plus™ - LS-B11843 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

GNAL Antibody - NBP1-00840 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: GNAL Antibody [NBP1-00840] - Extracts from LOVO cells.

GNAL Antibody - NBP1-32225 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GNAL Antibody [NBP1-32225] - Sample(30 ug of whole cell lysate)A:Raji 7. 5% SDS PAGE, antibody diluted at 1:1000.

GNAL Antibody - H00002774-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: GNAL Antibody [H00002774-A01] - GNAL polyclonal antibody (A01), Lot # 050926JCO1 Western Blot analysis of GNAL expression in MCF-7 ( Cat # L046V1 ).

GNAL Antibody - H00002774-B02P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: GNAL Antibody [H00002774-B02P] - Analysis of GNAL expression in transfected 293T cell line by GNAL polyclonal antibody. Lane 1: GNAL transfected lysate(52.50 KDa). Lane 2: Non-transfected lysate.

GNAL Antibody - NBP1-68534 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: GNAL Antibody [NBP1-68534] - Analysis of extracts from LOVO cells, using GNAL Antibody. The lane on the right is treated with the synthesized peptide.

Rabbit Anti-GNAL Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12003R-A350 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-GNAL Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12003R-A488 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-GNAL Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12003R-A555 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-GNAL Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12003R-A647 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-GNAL Polyclonal Antibody, Cy3 Conjugated - bs-12003R-Cy3 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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