| Gene Symbol |
DNASE1
|
| Entrez Gene |
1773
|
| Alt Symbol |
DNL1, DRNI
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
deoxyribonuclease I
|
| Other Description |
DNase I, lysosomal|Dornase alfa|deoxyribonuclease-1|human urine deoxyribonuclease I
|
| Swissprots |
B4DV35 Q14UU9 Q14UV0 P24855
|
| Accessions |
AAC24721 AIQ84312 AIQ84313 AIQ84314 AIQ84315 AIQ84316 BAA11841 CCQ43307 EAW85343 EAW85344 P24855 AB188151 BAE96964 AB188152 BAE96965 AI378682 AJ298844 CAC12813 AK095412 AK126850 AK300914 BAG62547 BC015002 BC029437 AAH29437 BC064332 BC095475 BX648257 BX648480 DQ579705 DQ584015 DQ892098 ABM83024 DQ895291 ABM86217 M55983 AAA63170 XM_005255148 XP_005255205 XM_005255149 XP_005255206 XM_006720854 XP_006720917 XM_011522393 XP_011520695 XM_011522394 XP_011520696 XM_011522395 XP_011520697 XM_011522396 XP_011520698 XM_011522397 XP_011520699 XM_011522398 XP_011520700 XR_243264 XR_932790 NM_005223 NP_005214
|
| Function |
Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted. Nucleus envelope. Note=Secretory protein, stored in zymogen granules and found in the nuclear envelope.
|
| Tissue Specificity |
Principally in tissues of the digestive system. Highest levels found in urine, but also relatively abundant in semen and saliva.
|
