Gene Symbol | MSLN |
---|---|
Entrez Gene | 10232 |
Alt Symbol | MPF, SMRP |
Species | Human |
Gene Type | protein-coding |
Description | mesothelin |
Other Description | CAK1 antigen|megakaryocyte potentiating factor|pre-pro-megakaryocyte-potentiating factor|soluble MPF mesothelin related protein |
Swissprots | Q96KJ5 Q9BTR2 Q9BR17 Q96GR6 D3DU65 Q9UCB2 Q4VQD5 Q9UK57 Q14859 Q13421 |
Accessions | AAK61253 EAW85719 EAW85720 EAW85721 Q13421 AF180951 AAF01409 AL545401 AY743922 AAV87530 BC003512 AAH03512 BC009272 AAH09272 CB266931 D49441 BAA08419 DQ891948 ABM82874 EU176658 ABW03459 U40434 AAC50348 XM_005255034 XP_005255091 XM_006720837 XP_006720900 XM_011522346 XP_011520648 XM_011522347 XP_011520649 XM_011522348 XP_011520650 XM_011522349 XP_011520651 XM_011522350 XP_011520652 NM_001177355 NP_001170826 NM_005823 NP_005814 NM_013404 NP_037536 |
Function | Membrane-anchored forms may play a role in cellular adhesion. |
Subcellular Location | Isoform 3: Secreted. |
Tissue Specificity | Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level). {ECO:0000269|PubMed:16857795, ECO:0000269|PubMed:7665620}. |