Gene Symbol | MSLN |
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Entrez Gene | 10232 |
Alt Symbol | MPF, SMRP |
Species | Human |
Gene Type | protein-coding |
Description | mesothelin |
Other Description | CAK1 antigen|megakaryocyte potentiating factor|pre-pro-megakaryocyte-potentiating factor|soluble MPF mesothelin related protein |
Swissprots | Q96KJ5 Q9BTR2 Q9BR17 Q96GR6 D3DU65 Q9UCB2 Q4VQD5 Q9UK57 Q14859 Q13421 |
Accessions | AAK61253 EAW85719 EAW85720 EAW85721 Q13421 AF180951 AAF01409 AL545401 AY743922 AAV87530 BC003512 AAH03512 BC009272 AAH09272 CB266931 D49441 BAA08419 DQ891948 ABM82874 EU176658 ABW03459 U40434 AAC50348 XM_005255034 XP_005255091 XM_006720837 XP_006720900 XM_011522346 XP_011520648 XM_011522347 XP_011520649 XM_011522348 XP_011520650 XM_011522349 XP_011520651 XM_011522350 XP_011520652 NM_001177355 NP_001170826 NM_005823 NP_005814 NM_013404 NP_037536 |
Function | Membrane-anchored forms may play a role in cellular adhesion. |
Subcellular Location | Isoform 3: Secreted. |
Tissue Specificity | Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level). {ECO:0000269|PubMed:16857795, ECO:0000269|PubMed:7665620}. |
Mesothelin CRISPR/Cas9 KO Plasmid (h) - sc-401170 from Santa Cruz Biotechnology
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Mesothelin HDR Plasmid (h) - sc-401170-HDR from Santa Cruz Biotechnology
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Mesothelin Double Nickase Plasmid (h) - sc-401170-NIC from Santa Cruz Biotechnology
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Mesothelin Double Nickase Plasmid (h2) - sc-401170-NIC-2 from Santa Cruz Biotechnology
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Mesothelin CRISPR Activation Plasmid (h) - sc-401170-ACT from Santa Cruz Biotechnology
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Mesothelin CRISPR Activation Plasmid (h2) - sc-401170-ACT-2 from Santa Cruz Biotechnology
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Mesothelin Lentiviral Activation Particles (h) - sc-401170-LAC from Santa Cruz Biotechnology
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Mesothelin Lentiviral Activation Particles (h2) - sc-401170-LAC-2 from Santa Cruz Biotechnology
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mesothelin siRNA (h) - sc-45386 from Santa Cruz Biotechnology
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mesothelin shRNA Plasmid (h) - sc-45386-SH from Santa Cruz Biotechnology
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mesothelin shRNA (h) Lentiviral Particles - sc-45386-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU030471 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14653 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14653 from Sigma-Aldrich
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MSLN siRNA (Human) - CRH6919 from Cohesion Biosciences
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Mesothelin RNAi - H00010232-R01 from Novus Biologicals
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Mesothelin RNAi - H00010232-R02 from Novus Biologicals
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shRNA set against Human MSLN (NM_005823.5) - SHH345740 from Creative biogene
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Human MSLN siRNA - orb267421 from Biorbyt
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MSLN shRNA Plasmid (Human) - CHH6919 from Cohesion Biosciences
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MSLN miRNA 3'UTR clone - MiUTR3H-03839 from Creative biogene
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MSLN miRNA 3'UTR clone - MiUTR3H-03840 from Creative biogene
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