| Gene Symbol | SOAT2 |
|---|---|
| Entrez Gene | 8435 |
| Alt Symbol | ACACT2, ACAT2, ARGP2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | sterol O-acyltransferase 2 |
| Other Description | ACAT-2|acyl Co-A: cholesterol acyltransferase 2|acyl coenzyme A:cholesterol acyltransferase 2|acyl-CoA:cholesterol acyltransferase 2|acyl-coenzyme A:cholesterol acyltransferase 2|cholesterol acyltransferase 2 |
| Swissprots | F5H7W4 O75908 Q4VBA1 Q9UNR2 Q96TD4 I6L9H9 Q4VB99 |
| Accessions | AAK18275 AAK48829 EAW96665 O75908 AF059203 AAC63998 AF099031 AAC78335 BC096090 AAH96090 BC096091 AAH96091 BC096092 AAH96092 BC099626 AAH99626 XM_011538849 XP_011537151 XM_011538850 XP_011537152 XM_011538851 XP_011537153 XR_944775 XR_944777 XR_944778 NM_003578 NP_003569 |
| Function | Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa. |
| Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expression seems confined in hepatocytes and enterocytes. {ECO:0000269|PubMed:16331323}. |
| Top Pathways | Steroid biosynthesis |