| Gene Symbol |
SOAT2
|
| Entrez Gene |
8435
|
| Alt Symbol |
ACACT2, ACAT2, ARGP2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sterol O-acyltransferase 2
|
| Other Description |
ACAT-2|acyl Co-A: cholesterol acyltransferase 2|acyl coenzyme A:cholesterol acyltransferase 2|acyl-CoA:cholesterol acyltransferase 2|acyl-coenzyme A:cholesterol acyltransferase 2|cholesterol acyltransferase 2
|
| Swissprots |
F5H7W4 O75908 Q4VBA1 Q9UNR2 Q96TD4 I6L9H9 Q4VB99
|
| Accessions |
AAK18275 AAK48829 EAW96665 O75908 AF059203 AAC63998 AF099031 AAC78335 BC096090 AAH96090 BC096091 AAH96091 BC096092 AAH96092 BC099626 AAH99626 XM_011538849 XP_011537151 XM_011538850 XP_011537152 XM_011538851 XP_011537153 XR_944775 XR_944777 XR_944778 NM_003578 NP_003569
|
| Function |
Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expression seems confined in hepatocytes and enterocytes. {ECO:0000269|PubMed:16331323}.
|
| Top Pathways |
Steroid biosynthesis
|
![Western Blot: SOAT 2 Overexpression Lysate (Adult Normal) [NBP2-10598] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SOAT 2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1084_SOAT%25202%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10598-img0001.jpg)