MBD6

Gene Symbol MBD6
Entrez Gene 114785
Alt Symbol -
Species Human
Gene Type protein-coding
Description methyl-CpG binding domain protein 6
Other Description methyl-CpG-binding domain protein 6|methyl-CpG-binding protein MBD6
Swissprots Q96DN6 Q96Q00 Q8NA81 Q8N3M0
Accessions EAW97024 EAW97025 EAW97026 Q96DN6 AB067474 BAB67780 AK056399 BAB71176 AK093078 BAC04045 AK296990 BAG59530 AL834230 CAD38908 BC034295 BC040149 BC051370 BC065530 AAH65530 CR627478 CAH10678 XM_005268617 XP_005268674 XM_005268618 XP_005268675 XM_005268620 XP_005268677 XM_006719217 XP_006719280 XM_006719218 XP_006719281 XM_011537851 XP_011536153 XR_429073 XR_429075 XR_429076 XR_429078 XR_429079 NM_052897 NP_443129
Function Binds to heterochromatin. Does not interact with either methylated or unmethylated DNA (in vitro).
Subcellular Location Nucleus {ECO:0000269|PubMed:20700456}. Chromosome {ECO:0000269|PubMed:20700456}. Note=Associated with pericentric heterochromatin in about 25% of the cells.

Anti-MBD6 antibody - ab37926 from Abcam

Prices $242.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab37926 stained human HeLa cells. The cells were 4% PFA fixed (10 min), permabilised in 0.1% PBS-Tween (20 min) and incubated with the antibody (ab37926, 1µg/ml) for 1h at room temperature. 1%BSA / 10% normal goat serum / 0.3M glycine was used to block non-specific protein-protein interactions. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red). DAPI was used to stain the cell nuclei (blue). This antibody also gave a positive IF result in HEK 293, HepG2 and MCF7 cells.  However, this Fast-Track antibody is not yet fully characterised.  This image represents inconclusive preliminary data.

Anti-MBD6 antibody - C-terminal - ab139067 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-MBD6 antibody - C-terminal (ab139067) at 1/100 dilution + mouse cerebellum tissue lysates at 35 µg

Anti-MBD6 Antibody (aa977-1003, Biotin) - LS-C262765 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MBD6 Antibody (aa977-1003, AP) - LS-C262763 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MBD6 Antibody (aa977-1003, FITC) - LS-C262766 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MBD6 Antibody (aa977-1003, PE) - LS-C262768 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MBD6 Antibody (aa977-1003, APC) - LS-C262764 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MBD6 Antibody (aa977-1003) - LS-C322884 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MBD6 Antibody (aa977-1003, Azide-free, HRP) - LS-C262767 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MBD6 Antibody (aa977-1003) - LS-C158106 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
MBD6 Antibody western blot of mouse cerebellum tissue lysates (35 ug/lane). The MBD6 antibody detected the MBD6 protein (arrow).

MBD6 Antibody - NBP2-38435 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: MBD6 Antibody [NBP2-38435] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleus.

MBD6 Antibody - NBP1-81363 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MBD6 antibody produced in rabbit - HPA038949 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MBD6: <B>Cat. No. HPA038949</B>: Immunohistochemical staining of human breast shows moderate cytoplasmic positivity in glandular cells.

ANTI-MBD6(C-TERMINAL) antibody produced in rabbit - SAB1305225 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MBD6 (C-term): <B>Cat. No. SAB1305225</B>: MBD6 Antibody (C-term) western blot analysis in Mouse cerebellum tissue lysates (35 μg/lane).

MBD6-Antibody-C-term - AP18913b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
MBD6 Antibody (C-term) (Cat. #AP18913b) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the MBD6 antibody detected the MBD6 protein (arrow).

MBD6 Antibody - C-terminal region (OAAB14451) - OAAB14451 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

MBD6, Polyclonal Antibody - MBS644824 from MyBioSource

Prices $550.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MBD6 (aa 977-1003) polyclonal antibody - DPABH-01836 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

MBD6, Polyclonal Antibody - MBS9215021 from MyBioSource

Prices $155.00, $340.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal

Anti-MBD6 antibody produced in rabbit - HPA038948 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MBD6: <B>Cat. No. HPA038948</B>: Immunohistochemical staining of human adrenal gland shows strong nuclear and cytoplasmic positivity in glandular cells.

MBD6 antibody - orb165845 from Biorbyt

Prices $187.00, $383.00
Sizes 80 μl (Trial size), 400 μl
Host Rabbit
Clonality Polyclonal
Clone RB30444

MBD6 Antibody - 60-195 from ProSci

Prices $375.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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