Gene Symbol | MBD6 |
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Entrez Gene | 114785 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | methyl-CpG binding domain protein 6 |
Other Description | methyl-CpG-binding domain protein 6|methyl-CpG-binding protein MBD6 |
Swissprots | Q96DN6 Q96Q00 Q8NA81 Q8N3M0 |
Accessions | EAW97024 EAW97025 EAW97026 Q96DN6 AB067474 BAB67780 AK056399 BAB71176 AK093078 BAC04045 AK296990 BAG59530 AL834230 CAD38908 BC034295 BC040149 BC051370 BC065530 AAH65530 CR627478 CAH10678 XM_005268617 XP_005268674 XM_005268618 XP_005268675 XM_005268620 XP_005268677 XM_006719217 XP_006719280 XM_006719218 XP_006719281 XM_011537851 XP_011536153 XR_429073 XR_429075 XR_429076 XR_429078 XR_429079 NM_052897 NP_443129 |
Function | Binds to heterochromatin. Does not interact with either methylated or unmethylated DNA (in vitro). |
Subcellular Location | Nucleus {ECO:0000269|PubMed:20700456}. Chromosome {ECO:0000269|PubMed:20700456}. Note=Associated with pericentric heterochromatin in about 25% of the cells. |
MBD6 CRISPR/Cas9 KO Plasmid (h) - sc-414039 from Santa Cruz Biotechnology
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MBD6 HDR Plasmid (h) - sc-414039-HDR from Santa Cruz Biotechnology
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MBD6 Double Nickase Plasmid (h) - sc-414039-NIC from Santa Cruz Biotechnology
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MBD6 Double Nickase Plasmid (h2) - sc-414039-NIC-2 from Santa Cruz Biotechnology
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MBD6 CRISPR Activation Plasmid (h) - sc-414039-ACT from Santa Cruz Biotechnology
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MBD6 CRISPR Activation Plasmid (h2) - sc-414039-ACT-2 from Santa Cruz Biotechnology
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MBD6 Lentiviral Activation Particles (h) - sc-414039-LAC from Santa Cruz Biotechnology
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MBD6 Lentiviral Activation Particles (h2) - sc-414039-LAC-2 from Santa Cruz Biotechnology
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MBD6 siRNA (h) - sc-96201 from Santa Cruz Biotechnology
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MBD6 shRNA Plasmid (h) - sc-96201-SH from Santa Cruz Biotechnology
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MBD6 shRNA (h) Lentiviral Particles - sc-96201-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU074081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13080 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13080 from Sigma-Aldrich
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MBD6 siRNA (Human) - CRJ4371 from Cohesion Biosciences
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MBD6 RNAi - H00114785-R01 from Novus Biologicals
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shRNA set against Human Mbd6 (NM_052897.3) - SHH338819 from Creative biogene
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shRNA set against Human MBD6(NM_052897.3) - SHH179471 from Creative biogene
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Human MBD6 siRNA - orb274872 from Biorbyt
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MBD6 shRNA Plasmid (Human) - CHJ4371 from Cohesion Biosciences
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MBD6 miRNA 3'UTR clone - MiUTR1H-06134 from Creative biogene
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