GLUL

Gene Symbol	GLUL
Entrez Gene	2752
Alt Symbol	GLNS, GS, PIG43, PIG59
Species	Human
Gene Type	protein-coding
Description	glutamate-ammonia ligase
Other Description	cell proliferation-inducing protein 59|glutamate decarboxylase|glutamine synthase|glutamine synthetase|proliferation-inducing protein 43
Swissprots	Q7Z3W4 Q8IZ17 Q499Y9 Q5T9Z1 P15104
Accessions	AAS57905 CCD35254 EAW91116 EAW91117 EAW91118 EAW91119 EAW91120 EAW91121 EAW91122 P15104 AI147221 AI286093 AK092874 BAG52617 AK122784 BAG53728 AK301600 BAG63088 AL161952 CAB82304 AW665656 AW954632 AY486122 AAS57904 AY513283 AAT08036 AY947343 AAY57874 BC010037 AAH10037 BC011700 AAH11700 BC011852 AAH11852 BC018992 AAH18992 BC031964 AAH31964 BC051726 AAH51726 BC127883 AAI27884 BF923451 BG771732 BI668874 BM662182 BM690132 BQ637044 BX537384 CAD97626 CD300750 CD688156 DA151535 DA322310 DA456371 DB317032 DQ893278 ABM84204 DQ896609 ABM87608 EU832658 ACE87749 EU832735 ACE87067 S70290 AAB30693 X59834 CAA42495 Y00387 CAA68457 XM_006711278 XP_006711341 NM_001033044 NP_001028216 NM_001033056 NP_001028228 NM_002065 NP_002056
Function	This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts. {ECO:0000250, ECO:0000269|PubMed:18662667}.
Subcellular Location	Cytoplasm. Mitochondrion {ECO:0000250}.
Top Pathways	Nitrogen metabolism, GABAergic synapse, Glutamatergic synapse, Arginine and proline metabolism, Glyoxylate and dicarboxylate metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Gl Syn CRISPR/Cas9 KO Plasmid (h) - sc-401090 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Gl Syn HDR Plasmid (h) - sc-401090-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Gl Syn Double Nickase Plasmid (h) - sc-401090-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Gl Syn Double Nickase Plasmid (h2) - sc-401090-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Gl Syn CRISPR Activation Plasmid (h) - sc-401090-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Gl Syn CRISPR Activation Plasmid (h2) - sc-401090-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Gl Syn Lentiviral Activation Particles (h) - sc-401090-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Gl Syn Lentiviral Activation Particles (h2) - sc-401090-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Gl Syn siRNA (h) - sc-35481 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Gl Syn shRNA Plasmid (h) - sc-35481-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Gl Syn shRNA (h) Lentiviral Particles - sc-35481-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Glutamine Synthetase RNAi - H00002752-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Glutamine Synthetase RNAi - H00002752-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Glutamine Synthetase RNAi - H00002752-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU115441 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9376 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9376 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1160 from Sigma-Aldrich Category ZFN Kit Prices $6,000.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1159 from Sigma-Aldrich Category ZFN Kit Prices $6,180.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10478 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr10478

GLUL siRNA (Human) - CRH1832 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

GLUL - MBS8213807 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Human GLUL siRNA - orb262334 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

GLUL shRNA Plasmid (Human) - CHH1832 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

GLUL miRNA 3'UTR clone - MiUTR4H-TG11316 from Creative biogene Species Reactivities Human

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