GLUL

Gene Symbol GLUL
Entrez Gene 2752
Alt Symbol GLNS, GS, PIG43, PIG59
Species Human
Gene Type protein-coding
Description glutamate-ammonia ligase
Other Description cell proliferation-inducing protein 59|glutamate decarboxylase|glutamine synthase|glutamine synthetase|proliferation-inducing protein 43
Swissprots Q7Z3W4 Q8IZ17 Q499Y9 Q5T9Z1 P15104
Accessions AAS57905 CCD35254 EAW91116 EAW91117 EAW91118 EAW91119 EAW91120 EAW91121 EAW91122 P15104 AI147221 AI286093 AK092874 BAG52617 AK122784 BAG53728 AK301600 BAG63088 AL161952 CAB82304 AW665656 AW954632 AY486122 AAS57904 AY513283 AAT08036 AY947343 AAY57874 BC010037 AAH10037 BC011700 AAH11700 BC011852 AAH11852 BC018992 AAH18992 BC031964 AAH31964 BC051726 AAH51726 BC127883 AAI27884 BF923451 BG771732 BI668874 BM662182 BM690132 BQ637044 BX537384 CAD97626 CD300750 CD688156 DA151535 DA322310 DA456371 DB317032 DQ893278 ABM84204 DQ896609 ABM87608 EU832658 ACE87749 EU832735 ACE87067 S70290 AAB30693 X59834 CAA42495 Y00387 CAA68457 XM_006711278 XP_006711341 NM_001033044 NP_001028216 NM_001033056 NP_001028228 NM_002065 NP_002056
Function This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts. {ECO:0000250, ECO:0000269|PubMed:18662667}.
Subcellular Location Cytoplasm. Mitochondrion {ECO:0000250}.
Top Pathways Nitrogen metabolism, GABAergic synapse, Glutamatergic synapse, Arginine and proline metabolism, Glyoxylate and dicarboxylate metabolism

Gl Syn (D-6) - sc-376767 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Gl Syn (D-6): sc-376767. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Gl Syn (E-2) - sc-398017 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Gl Syn (E-2): sc-398017. Western blot analysis of Gl Syn expression in KNRK (A), Jurkat (B) and HeLa (C) whole cell lysates and mouse brain (D) and human liver (E) tissue extracts.

Gl Syn (F-4) - sc-398034 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Gl Syn (F-4): sc-398034. Western blot analysis of Gl Syn expression in Jurkat whole cell lysate (A) and human liver tissue extract (B).

Gl Syn (G-20) - sc-32560 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Gl Syn (G-20): sc-32560. Western blot analysis of Gl Syn expression in non-transfected: sc-117752 (A) and mouse Gl Syn transfected: sc-120492 (B) 293T whole cell lysates.

Gl Syn (E-21) - sc-32557 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Gl Syn (E-21): sc-32557. Western blot analysis of Gl Syn expression in mouse brain (A) and rat brain (B) tissue extracts.

Gl Syn (E-4) - sc-74430 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GI Syn (E-4): sc-74430. Western blot analysis of GI Syn expression in Hep G2 (A) and KNRK (B) whole cell lysates and mouse brain (C), rat brain (D) and rat liver (E) tissue extracts.

Gl Syn (C-20) - sc-6640 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GI Syn (C-20): sc-6640. Western blot analysis of glutamine synthetase expression in rat brain extract.

Gl Syn (FL-373) - sc-9067 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Gl Syn (FL-373): sc-9067. Western blot analysis of Gl Syn expression in non-transfected: sc-117752 (A) and mouse Gl Syn transfected: sc-120492 (B) 293T whole cell lysates.

Anti-Glutamine Synthetase antibody - ab181625 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-Glutamine Synthetase antibody (ab181625) at 1/1000 dilution + Glutamine Synthetase at 0.05 µgSecondaryPeroxidase anti-Goat at 1/40000 dilution

Anti-Glutamine Synthetase antibody [1F4] - ab118059 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F4
All lanes : Anti-Glutamine Synthetase antibody [1F4] (ab118059) at 1/2000 dilutionLane 1 : HEK293T cell lyaste, transfected with pCMV6-ENTRY control Lane 2 : HEK293T cell lysate, transfected with pCMV6-ENTRY Glutamine Synthetase Lysates/proteins at 5 µg per lane.

Anti-Glutamine Synthetase antibody [27D10] - ab21254 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 27D10
ab21254 staining human Glutamine Synthetase in Bosc23 cell lysates transfected with myc-Glutamine Synthetase by Immunoprecipitation.Lane 1: Transfected proteinLane 2: Result of precipitates

Anti-Glutamine Synthetase antibody [6/Glutamine Synthetase] - ab125724 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6/Glutamine Synthetase
ab125724 at 1/150 dilution staining Glutamine Synthetase in Paraffin-embedded Human liver tissue by Immunohistochemistry.

Anti-Glutamine Synthetase antibody [8G9] - ab21256 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8G9
ab21256 staining human Glutamine Synthetase in Bosc23 cell lysates transfected with myc-Glutamine Synthetase by Immunoprecipitation.Lane 1: Transfected proteinLane 2: Result of precipitates

Anti-Glutamine Synthetase antibody (Biotin) - ab181726 from Abcam

Prices $372.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-Glutamine Synthetase antibody (Biotin) - ab34545 from Abcam

Prices $359.00
Sizes 5 mg
Host Goat
Clonality Polyclonal

Anti-Glutamine Synthetase antibody [EPR13021] - ab178422 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13021
All lanes : Anti-Glutamine Synthetase antibody [EPR13021] (ab178422) at 1/1000 dilutionLane 1 : Human fetal liver lysatesLane 2 : HeLa cell lysatesLane 3 : HT29 cell lysatesLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-Glutamine Synthetase antibody [EPR13022(B)] - ab176562 from Abcam

Prices $99.00
Sizes 10 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13022(B)
All lanes : Anti-Glutamine Synthetase antibody [EPR13022(B)] (ab176562) at 1/1000 dilutionLane 1 : Human fetal liver lysateLane 2 : Jurkat cell lysateLane 3 : HeLa cell lysateLysates/proteins at 10 µg per lane.developed using the ECL technique

Anti-Glutamine Synthetase antibody [EPR16661] - ab197024 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16661
All lanes : Anti-Glutamine Synthetase antibody [EPR16661] (ab197024) at 1/1000 dilutionLane 1 : Human fetal liver lysateLane 2 : HeLa (Human epithelial cells from cervix adenocarcinoma) lysateLysates/proteins at 20 µg per lane.SecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-Glutamine Synthetase antibody - N-terminal - ab135622 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Glutamine Synthetase antibody - N-terminal (ab135622) at 1/100 dilution + Mouse cerebellum tissue lysates at 35 µg

Anti-GLUL / Glutamine Synthetase Antibody - LS-C23896 from LifeSpan Bioscience

Prices $325.00
Sizes 1 ml
Host Goat
Clonality Polyclonal

Anti-GLUL / Glutamine Synthetase Antibody - LS-C23897 from LifeSpan Bioscience

Prices $285.00
Sizes 10 mg
Host Goat
Clonality Polyclonal

Anti-GLUL / Glutamine Synthetase Antibody - LS-C66673 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GLUL / Glutamine Synthetase Antibody - LS-C66672 from LifeSpan Bioscience

Prices $485.00
Sizes 1 ml
Host Goat
Clonality Polyclonal

Anti-GLUL / Glutamine Synthetase Antibody - LS-C129311 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-GLUL / Glutamine Synthetase Antibody - LS-C129312 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
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