| Gene Symbol |
TAF1B
|
| Entrez Gene |
9014
|
| Alt Symbol |
MGC:9349, RAF1B, RAFI63, SL1, TAFI63
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
|
| Other Description |
RNA polymerase I-specific TBP-associated factor 63 kDa|SL1, 63kD subunit|TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kD|TATA box-binding protein-associated factor 1B|TATA box-binding protein-associated factor RNA polymerase I subunit B|TBP-associated factor 1B|transcription initiation factor SL1/TIF-IB subunit B
|
| Swissprots |
F8WD72 Q53T94 Q8WVC3 Q15574 B4DI42
|
| Accessions |
AAX93272 EAX00974 EAX00975 EAX00976 Q53T94 AA746267 AK026521 AK295402 BAG58354 AK308070 AK309751 AK315098 BC018137 AAH18137 CA423871 DA910748 DQ894659 ABM85585 L39061 AAA62863 XM_011510410 XP_011508712 XM_011510411 XP_011508713 XM_011510412 XP_011508714 XM_011510413 XP_011508715 NM_005680 NP_005671
|
| Function |
Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during trancription initiation such as preinitiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3. {ECO:0000269|PubMed:15970593, ECO:0000269|PubMed:21921198, ECO:0000269|PubMed:21921199, ECO:0000269|PubMed:7491500, ECO:0000269|PubMed:7801123, ECO:0000269|PubMed:7801130}.
|
| Subcellular Location |
Nucleus, nucleolus.
|
