LINGO1

Gene Symbol	LINGO1
Entrez Gene	84894
Alt Symbol	LERN1, LRRN6A, UNQ201
Species	Human
Gene Type	protein-coding
Description	leucine rich repeat and Ig domain containing 1
Other Description	leucine rich repeat neuronal 6A|leucine-rich repeat and immunoglobulin domain-containing protein 1|leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1|leucine-rich repeat neuronal protein 1
Swissprots	Q8N3K5 D3DW80 Q6VVG2 Q6UXM3 Q6VVG0 Q6NUK3 Q96K52 Q6VVG1 Q96FE5
Accessions	EAW99195 EAW99196 EAW99197 EAW99198 Q96FE5 AK027500 BAB55157 AK291363 BAF84052 AL109677 AL834260 CAD38935 AY324320 AAQ97216 AY324322 AAQ97217 AY324323 AAQ97218 AY358284 AAQ88651 BC011057 AAH11057 BC068558 AAH68558 BI523562 BI669707 BI825536 BX355455 DA150164 DA182630 DA183673 DA232085 DA328735 DA410114 DA483616 DA494936 DA525603 DA787289 DB165168 H11343 HY342106 XM_011522117 XP_011520419 XM_011522118 XP_011520420 NM_001301186 NP_001288115 NM_001301187 NP_001288116 NM_001301189 NP_001288118 NM_001301191 NP_001288120 NM_001301192 NP_001288121 NM_001301194 NP_001288123 NM_001301195 NP_001288124 NM_001301197 NP_001288126 NM_001301198 NP_001288127 NM_001301199 NP_001288128 NM_001301200 NP_001288129 NM_032808 NP_116197
Function	Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity	Expressed exclusively in the central nervous system. Highest level in the in amygdala, hippocampus, thalamus and cerebral cortex. In the rest of the brain a basal expression seems to be always present. Up-regulated in substantia nigra neurons from Parkinson disease patients. {ECO:0000269|PubMed:14686891, ECO:0000269|PubMed:15895088, ECO:0000269|PubMed:17726113}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Lingo1 full length protein - ab153558 from Abcam Category Protein Source Wheat germ Species Human

Human Lingo1 peptide - ab25890 from Abcam Category Peptide

Human Lingo1 protein fragment - ab202603 from Abcam Category Protein Source E. coli Species Human

LINGO1 Antibody Blocking Peptide - LS-E7734 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LINGO1 Antibody Blocking Peptide - LS-E8832 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LINGO1 Antibody Blocking Peptide - LS-E8833 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LINGO1 Antibody Blocking Peptide - LS-E7458 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LINGO1 Antibody Blocking Peptide - LS-E29606 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

LINGO1 Antibody Blocking Peptide - LS-E29608 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

LINGO1 Antibody Blocking Peptide - LS-E29609 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human LINGO-1 Protein - H00084894-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

LINGO-1 Peptide - P2468 from Novus Biologicals Category Peptide Species Human

LINGO1-Antibody-N-term-Blocking-Peptide - BP7284d from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

LINGO1-Antibody-N-term-Blocking-Peptide - BP7284a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Lingo-1 peptide - orb72927 from Biorbyt Category Peptide Prices $238.00 Sizes 500 µg

LINGO protein (His tag) - 80R-4145 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

LINGO1 (241-370, His-tag) - AR51831PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

LINGO1 (241-370, His-tag) - AR51831PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

LINGO1 - H00084894-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

LINGO1 - H00084894-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

LINGO1 fusion protein - ag13702 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

LINGO1 fusion protein - Ag13597 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

LINGO1 fusion protein - Ag13553 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human Leucine-rich repeat and immunoglobulin-like domain-containing - CSB-YP839321HU CSB-EP839321HU CSB-BP839321HU CSB-MP839321HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

LINGO, 241-337aa, Human, His tag, E.coli (Denatured) - ATGP3011 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

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