| Gene Symbol |
NDUFS6
|
| Entrez Gene |
4726
|
| Alt Symbol |
CI-13kA, CI-13kD-A, CI13KDA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
|
| Other Description |
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial|NADH-ubiquinone oxidoreductase 13 kDa-A subunit|NADH:ubiquinone oxidoreductase NDUFS6 subunit|complex I 13kDa subunit A|complex I, mitochondrial respiratory chain, 13-kD subunit
|
| Swissprots |
O75380
|
| Accessions |
EAX08142 EAX08143 O75380 AF044959 AAC27799 AK022503 BAG51079 BC038664 AAH38664 BC046155 AAH46155 BE900424 BG706812 BM172493 BM759028 BM764340 CN285188 CR456880 CAG33161 HQ257915 ADR82670 NM_004553 NP_004544
|
| Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
|
| Subcellular Location |
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|