Gene Symbol | NDUFS6 |
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Entrez Gene | 4726 |
Alt Symbol | CI-13kA, CI-13kD-A, CI13KDA |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) |
Other Description | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial|NADH-ubiquinone oxidoreductase 13 kDa-A subunit|NADH:ubiquinone oxidoreductase NDUFS6 subunit|complex I 13kDa subunit A|complex I, mitochondrial respiratory chain, 13-kD subunit |
Swissprots | O75380 |
Accessions | EAX08142 EAX08143 O75380 AF044959 AAC27799 AK022503 BAG51079 BC038664 AAH38664 BC046155 AAH46155 BE900424 BG706812 BM172493 BM759028 BM764340 CN285188 CR456880 CAG33161 HQ257915 ADR82670 NM_004553 NP_004544 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFS6 CRISPR/Cas9 KO Plasmid (h) - sc-410904 from Santa Cruz Biotechnology
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NDUFS6 HDR Plasmid (h) - sc-410904-HDR from Santa Cruz Biotechnology
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NDUFS6 Double Nickase Plasmid (h) - sc-410904-NIC from Santa Cruz Biotechnology
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NDUFS6 Double Nickase Plasmid (h2) - sc-410904-NIC-2 from Santa Cruz Biotechnology
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NDUFS6 CRISPR Activation Plasmid (h) - sc-410904-ACT from Santa Cruz Biotechnology
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NDUFS6 CRISPR Activation Plasmid (h2) - sc-410904-ACT-2 from Santa Cruz Biotechnology
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NDUFS6 Lentiviral Activation Particles (h) - sc-410904-LAC from Santa Cruz Biotechnology
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NDUFS6 Lentiviral Activation Particles (h2) - sc-410904-LAC-2 from Santa Cruz Biotechnology
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NDUFS6 siRNA (h) - sc-91874 from Santa Cruz Biotechnology
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NDUFS6 shRNA Plasmid (h) - sc-91874-SH from Santa Cruz Biotechnology
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NDUFS6 shRNA (h) Lentiviral Particles - sc-91874-V from Santa Cruz Biotechnology
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NDUFS6 RNAi - H00004726-R01 from Novus Biologicals
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MISSION® esiRNA - EHU056551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15171 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15171 from Sigma-Aldrich
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NDUFS6 siRNA (Human) - CRH3139 from Cohesion Biosciences
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NDUFS6 shRNA Plasmid (Human) - CHH3139 from Cohesion Biosciences
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