| Gene Symbol |
FOXH1
|
| Entrez Gene |
8928
|
| Alt Symbol |
FAST-1, FAST1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
forkhead box H1
|
| Other Description |
TGF-beta/activin signal transducer|fast-2|forkhead activin signal transducer 2|forkhead activin signal transducer-1|forkhead box protein H1|hFAST-1
|
| Swissprots |
D3DWM4 O75593
|
| Accessions |
EAW82083 EAW82084 O75593 AF076292 AAC34303 BC051376 BC065377 AAH65377 BC111604 AAI11605 BE550635 CX782591 NM_003923 NP_003914
|
| Function |
Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element). {ECO:0000269|PubMed:9702198}.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:9702198}.
|