| Gene Symbol |
DMRT2
|
| Entrez Gene |
10655
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
doublesex and mab-3 related transcription factor 2
|
| Other Description |
DSXL-2|doublesex- and mab-3-related transcription factor 2|doublesex-like 2 protein|terra-like protein
|
| Swissprots |
Q9NQR6 Q9NPG6 B9EGJ1 B1ANC0 Q9Y5R5
|
| Accessions |
EAW58816 EAW58817 EAW58818 Q9Y5R5 AA771859 AF130729 AAD40475 AF284221 AAF86289 AF284222 AAF86290 AF284223 AAF86291 AF284224 AAF86293 AF284225 AAF86295 AK290794 BAF83483 BC030204 AAH30204 BC136493 AAI36494 BP274385 BX107686 BX647565 CAI46061 Y19052 CAB59891 XM_006716717 XP_006716780 XM_006716718 XP_006716781 XM_011517687 XP_011515989 XM_011517689 XP_011515991 XM_011517690 XP_011515992 XM_011517691 XP_011515993 XM_011517692 XP_011515994 XM_011517693 XP_011515995 XM_011517694 XP_011515996 XM_011517695 XP_011515997 XM_011517696 XP_011515998 NM_001130865 NP_001124337 NM_006557 NP_006548 NM_181872 NP_870987
|
| Function |
Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00070}.
|
| Tissue Specificity |
Expressed in testis, kidney and skeletal muscle.
|
![Western Blot: DMRT2 Overexpression Lysate (Adult Normal) [NBP2-04871] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DMRT2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5877_DMRT2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04871-img0001.jpg)