| Gene Symbol |
Tacr1
|
| Entrez Gene |
24807
|
| Alt Symbol |
Tac1r
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
tachykinin receptor 1
|
| Other Description |
NK-1 receptor|NK-1R|SPR|neurokinin 1 receptor|substance p receptor|substance-P receptor
|
| Swissprots |
P14600
|
| Accessions |
AAA42176 EDL91094 EDL91095 P14600 J05097 AAA42175 M31477 AAB59726 NM_012667 NP_036799
|
| Function |
This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Calcium signaling pathway, Measles, Neuroactive ligand-receptor interaction
|