Gene Symbol | Tacr1 |
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Entrez Gene | 24807 |
Alt Symbol | Tac1r |
Species | Rat |
Gene Type | protein-coding |
Description | tachykinin receptor 1 |
Other Description | NK-1 receptor|NK-1R|SPR|neurokinin 1 receptor|substance p receptor|substance-P receptor |
Swissprots | P14600 |
Accessions | AAA42176 EDL91094 EDL91095 P14600 J05097 AAA42175 M31477 AAB59726 NM_012667 NP_036799 |
Function | This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Calcium signaling pathway, Measles, Neuroactive ligand-receptor interaction |
CompoZr® Knockout ZFN Kit - CKOZFN63804 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND63804 from Sigma-Aldrich
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TACR1 siRNA (Rat) - CRR0306 from Cohesion Biosciences
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TACR1 - MBS8220020 from MyBioSource
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shRNA set against Rat TACR1 (NM_012667.2) - SHH422468 from Creative biogene
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shRNA set against Rat Tacr1(NM_012667.2) - SHL053616 from Creative biogene
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Rat TACR1 siRNA - orb295155 from Biorbyt
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TACR1 shRNA Plasmid (Rat) - CHR0306 from Cohesion Biosciences
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TACR1 miRNA 3'UTR clone - MiUTR1R-07874 from Creative biogene
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