Gene Symbol | POMT2 |
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Entrez Gene | 29954 |
Alt Symbol | LGMD2N, MDDGA2, MDDGB2, MDDGC2 |
Species | Human |
Gene Type | protein-coding |
Description | protein-O-mannosyltransferase 2 |
Other Description | dolichyl-phosphate-mannose--protein mannosyltransferase 2|protein O-mannosyl-transferase 2 |
Swissprots | Q9P1W0 Q9UKY4 Q9P1W2 Q9NSG6 |
Accessions | AAF62558 AAF63184 EAW81276 EAW81277 Q9UKY4 AB209114 BAD92351 AF105020 AAF14118 AI927974 AK023804 AK025962 AL049462 AL353956 CAB89256 AL554279 AY090480 AAM12046 BC031651 AAH31651 BE797202 BM127609 BM724049 BX248027 CAD62348 CB148531 CR627447 CAH10531 DA056935 DB456599 XM_011536675 XP_011534977 XM_011536676 XP_011534978 XM_011536677 XP_011534979 XM_011536678 XP_011534980 XM_011536679 XP_011534981 XM_011536680 XP_011534982 XR_943416 NM_013382 NP_037514 |
Function | Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. {ECO:0000269|PubMed:14699049}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12460945, ECO:0000269|PubMed:14699049}; Multi- pass membrane protein {ECO:0000269|PubMed:12460945, ECO:0000269|PubMed:14699049}. |
Tissue Specificity | Highly expressed in testis; detected at low levels in most tissues. |
Top Pathways | Other types of O-glycan biosynthesis |
Human POMT2 full length protein - ab162286 from Abcam
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Human POMT2 protein fragment - ab162287 from Abcam
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POMT2 Antibody Blocking Peptide - LS-E4970 from LifeSpan Bioscience
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POMT2 Antibody Blocking Peptide - LS-E17063 from LifeSpan Bioscience
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Recombinant Human POMT2 Protein - H00029954-P01 from Novus Biologicals
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Recombinant Human POMT2 Protein - H00029954-Q01 from Novus Biologicals
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POMT2-Antibody-C-term-Blocking-Peptide - BP17363b from Abgent, a WuXi AppTec company
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POMT2 Blocking Peptide - 33R-7995 from Fitzgerald
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POMT2 Blocking Peptide - 33R-1266 from Fitzgerald
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POMT2 - H00029954-P01-10 from Acris Antibodies
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POMT2 - H00029954-P01-25 from Acris Antibodies
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POMT2 - H00029954-Q01-10 from Acris Antibodies
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POMT2 - H00029954-Q01-25 from Acris Antibodies
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POMT2 fusion protein - Ag4001 from Proteintech Group
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POMT2 fusion protein - Ag14409 from Proteintech Group
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Recombinant Human POMT2, GST-tagged - POMT2-1857H from Creative Biomart
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POMT2 Protein - NBP1-86152PEP from Novus Biologicals
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POMT2 Peptide, Human - M34GP12123H from Creative Peptides
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