Gene Symbol | POMT2 |
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Entrez Gene | 29954 |
Alt Symbol | LGMD2N, MDDGA2, MDDGB2, MDDGC2 |
Species | Human |
Gene Type | protein-coding |
Description | protein-O-mannosyltransferase 2 |
Other Description | dolichyl-phosphate-mannose--protein mannosyltransferase 2|protein O-mannosyl-transferase 2 |
Swissprots | Q9P1W0 Q9UKY4 Q9P1W2 Q9NSG6 |
Accessions | AAF62558 AAF63184 EAW81276 EAW81277 Q9UKY4 AB209114 BAD92351 AF105020 AAF14118 AI927974 AK023804 AK025962 AL049462 AL353956 CAB89256 AL554279 AY090480 AAM12046 BC031651 AAH31651 BE797202 BM127609 BM724049 BX248027 CAD62348 CB148531 CR627447 CAH10531 DA056935 DB456599 XM_011536675 XP_011534977 XM_011536676 XP_011534978 XM_011536677 XP_011534979 XM_011536678 XP_011534980 XM_011536679 XP_011534981 XM_011536680 XP_011534982 XR_943416 NM_013382 NP_037514 |
Function | Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. {ECO:0000269|PubMed:14699049}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12460945, ECO:0000269|PubMed:14699049}; Multi- pass membrane protein {ECO:0000269|PubMed:12460945, ECO:0000269|PubMed:14699049}. |
Tissue Specificity | Highly expressed in testis; detected at low levels in most tissues. |
Top Pathways | Other types of O-glycan biosynthesis |
POMT2 (G-3) - sc-393487 from Santa Cruz Biotechnology
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POMT2 (N-18) - sc-48919 from Santa Cruz Biotechnology
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POMT2 (N-16) - sc-48918 from Santa Cruz Biotechnology
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POMT2 (K-19) - sc-48917 from Santa Cruz Biotechnology
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POMT2 (H-52) - sc-98909 from Santa Cruz Biotechnology
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Anti-POMT2 antibody - ab76396 from Abcam
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Anti-POMT2 antibody - ab57135 from Abcam
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Anti-POMT2 antibody - C-terminal - ab173085 from Abcam
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Anti-POMT2 Antibody (aa540-567, AP) - LS-C216891 from LifeSpan Bioscience
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Anti-POMT2 Antibody (aa540-567, Biotin) - LS-C216893 from LifeSpan Bioscience
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Anti-POMT2 Antibody (aa540-567, APC) - LS-C216892 from LifeSpan Bioscience
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Anti-POMT2 Antibody (aa540-567, Azide-free, HRP) - LS-C216895 from LifeSpan Bioscience
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Anti-POMT2 Antibody (aa540-567, PE) - LS-C216896 from LifeSpan Bioscience
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Anti-POMT2 Antibody (aa540-567, FITC) - LS-C216894 from LifeSpan Bioscience
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Anti-POMT2 Antibody (aa539-567) - LS-C324180 from LifeSpan Bioscience
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Anti-POMT2 Antibody (aa434-483) - LS-C80962 from LifeSpan Bioscience
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Anti-POMT2 Antibody (aa351-400) - LS-C80963 from LifeSpan Bioscience
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Anti-POMT2 Antibody (aa540-567) - LS-C158699 from LifeSpan Bioscience
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POMT2 Antibody - NBP1-60068 from Novus Biologicals
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POMT2 Antibody - NBP1-59469 from Novus Biologicals
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POMT2 Antibody - NBP1-86152 from Novus Biologicals
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POMT2 Antibody (1D9) - H00029954-M01 from Novus Biologicals
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POMT2 Antibody - H00029954-A01 from Novus Biologicals
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Anti-POMT2 antibody produced in rabbit - HPA003663 from Sigma-Aldrich
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Anti-POMT2 (AB1) antibody produced in rabbit - AV46939 from Sigma-Aldrich
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