| Gene Symbol |
DNAAF2
|
| Entrez Gene |
55172
|
| Alt Symbol |
C14orf104, CILD10, KTU, PF13
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dynein, axonemal, assembly factor 2
|
| Other Description |
dynein assembly factor 2, axonemal|kintoun|protein kintoun
|
| Swissprots |
Q86TY8 B9WS54 Q969Z5 Q9NVR5 C0JAP7 Q86TR1
|
| Accessions |
EAW65755 EAW65756 EAW65757 Q9NVR5 AK001425 BAA91684 BC011400 AAH11400 BC013322 AAH13322 BX092175 BX248264 CAD62592 BX248765 CAD66572 FJ158843 ACN30493 NM_001083908 NP_001077377 NM_018139 NP_060609
|
| Function |
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:19052621}. Note=Localizes in the apical cytoplasm around the gamma-tubulin- positive pericentriolar region, not in the cilia.
|