Gene Symbol | DNAAF2 |
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Entrez Gene | 55172 |
Alt Symbol | C14orf104, CILD10, KTU, PF13 |
Species | Human |
Gene Type | protein-coding |
Description | dynein, axonemal, assembly factor 2 |
Other Description | dynein assembly factor 2, axonemal|kintoun|protein kintoun |
Swissprots | Q86TY8 B9WS54 Q969Z5 Q9NVR5 C0JAP7 Q86TR1 |
Accessions | EAW65755 EAW65756 EAW65757 Q9NVR5 AK001425 BAA91684 BC011400 AAH11400 BC013322 AAH13322 BX092175 BX248264 CAD62592 BX248765 CAD66572 FJ158843 ACN30493 NM_001083908 NP_001077377 NM_018139 NP_060609 |
Function | Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:19052621}. Note=Localizes in the apical cytoplasm around the gamma-tubulin- positive pericentriolar region, not in the cilia. |
C14orf104 CRISPR/Cas9 KO Plasmid (h) - sc-412468 from Santa Cruz Biotechnology
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C14orf104 HDR Plasmid (h) - sc-412468-HDR from Santa Cruz Biotechnology
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C14orf104 Double Nickase Plasmid (h) - sc-412468-NIC from Santa Cruz Biotechnology
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C14orf104 Double Nickase Plasmid (h2) - sc-412468-NIC-2 from Santa Cruz Biotechnology
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C14orf104 CRISPR Activation Plasmid (h) - sc-412468-ACT from Santa Cruz Biotechnology
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C14orf104 CRISPR Activation Plasmid (h2) - sc-412468-ACT-2 from Santa Cruz Biotechnology
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C14orf104 Lentiviral Activation Particles (h) - sc-412468-LAC from Santa Cruz Biotechnology
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C14orf104 Lentiviral Activation Particles (h2) - sc-412468-LAC-2 from Santa Cruz Biotechnology
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C14orf104 siRNA (h) - sc-92288 from Santa Cruz Biotechnology
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C14orf104 shRNA Plasmid (h) - sc-92288-SH from Santa Cruz Biotechnology
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C14orf104 shRNA (h) Lentiviral Particles - sc-92288-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU099061 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4308 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4308 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03388 from Sigma-Aldrich
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DNAAF2 siRNA (Human) - CRJ0525 from Cohesion Biosciences
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DNAAF2 - MBS8225934 from MyBioSource
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shRNA set against Human Dnaaf2 (NM_018139.2) - SHH279053 from Creative biogene
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shRNA set against Human C14orf104(NM_018139.2) - SHG114571 from Creative biogene
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Human DNAAF2 siRNA - orb271026 from Biorbyt
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DNAAF2 shRNA Plasmid (Human) - CHJ0525 from Cohesion Biosciences
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DNAAF2 miRNA 3'UTR clone - MiUTR1H-01085 from Creative biogene
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DNAAF2 miRNA 3'UTR clone - MiUTR3H-12487 from Creative biogene
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