| Gene Symbol |
Lage3
|
| Entrez Gene |
66192
|
| Alt Symbol |
1110049G11Rik, Eso3, Itba2
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
L antigen family, member 3
|
| Other Description |
EKC/KEOPS complex subunit Lage3|ITBA2 protein homolog
|
| Swissprots |
Q9CR70
|
| Accessions |
CAM24348 CAM24349 EDL29819 Q9CR70 AK002539 BAB22174 AK004210 BAB23222 AK134624 BC027305 AAH27305 NM_025410 NP_079686
|
| Function |
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}.
|