Gene Symbol | Lage3 |
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Entrez Gene | 66192 |
Alt Symbol | 1110049G11Rik, Eso3, Itba2 |
Species | Mouse |
Gene Type | protein-coding |
Description | L antigen family, member 3 |
Other Description | EKC/KEOPS complex subunit Lage3|ITBA2 protein homolog |
Swissprots | Q9CR70 |
Accessions | CAM24348 CAM24349 EDL29819 Q9CR70 AK002539 BAB22174 AK004210 BAB23222 AK134624 BC027305 AAH27305 NM_025410 NP_079686 |
Function | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. |
LAGE-3 CRISPR/Cas9 KO Plasmid (m) - sc-425876 from Santa Cruz Biotechnology
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LAGE-3 HDR Plasmid (m) - sc-425876-HDR from Santa Cruz Biotechnology
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LAGE-3 Double Nickase Plasmid (m) - sc-425876-NIC from Santa Cruz Biotechnology
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LAGE-3 Double Nickase Plasmid (m2) - sc-425876-NIC-2 from Santa Cruz Biotechnology
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LAGE-3 CRISPR Activation Plasmid (m) - sc-425876-ACT from Santa Cruz Biotechnology
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LAGE-3 CRISPR Activation Plasmid (m2) - sc-425876-ACT-2 from Santa Cruz Biotechnology
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LAGE-3 Lentiviral Activation Particles (m) - sc-425876-LAC from Santa Cruz Biotechnology
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LAGE-3 Lentiviral Activation Particles (m2) - sc-425876-LAC-2 from Santa Cruz Biotechnology
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LAGE-3 siRNA (m) - sc-146637 from Santa Cruz Biotechnology
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LAGE-3 shRNA Plasmid (m) - sc-146637-SH from Santa Cruz Biotechnology
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LAGE-3 shRNA (m) Lentiviral Particles - sc-146637-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU091211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN34591 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND34591 from Sigma-Aldrich
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LAGE3 siRNA (Mouse) - CRM6487 from Cohesion Biosciences
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shRNA set against Mouse LAGE3 (NM_025410.2) - SHH328163 from Creative biogene
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shRNA set against Mouse Lage3(NM_025410.2) - SHH141095 from Creative biogene
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Mouse LAGE3 siRNA - orb285963 from Biorbyt
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LAGE3 shRNA Plasmid (Mouse) - CHM6487 from Cohesion Biosciences
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LAGE3 miRNA 3'UTR clone - MiUTR1M-06506 from Creative biogene
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