Gene Symbol | ANKRD13B |
---|---|
Entrez Gene | 124930 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ankyrin repeat domain 13B |
Other Description | ankyrin repeat domain-containing protein 13B |
Swissprots | Q86YJ7 Q8N7S9 |
Accessions | EAW51199 EAW51200 EAW51201 EAW51202 EAW51203 Q86YJ7 AK000425 AK092673 BAG52589 AK097716 BAC05148 AK098421 BAC05304 BC032554 AAH32554 BC062597 AAH62597 BG029526 DA445860 XM_005257920 XP_005257977 XM_011524319 XP_011522621 XM_011524320 XP_011522622 XM_011524321 XP_011522623 XR_934365 XR_934366 NM_152345 NP_689558 |
Function | Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand- activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. {ECO:0000269|PubMed:22298428}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:22298428}. Late endosome {ECO:0000269|PubMed:22298428}. Early endosome {ECO:0000269|PubMed:22298428}. Note=Interaction with EGFR may enhance association with the cell membrane. |
ANKRD13B CRISPR/Cas9 KO Plasmid (h) - sc-414227 from Santa Cruz Biotechnology
|
||||||||
ANKRD13B HDR Plasmid (h) - sc-414227-HDR from Santa Cruz Biotechnology
|
||||||||
ANKRD13B Double Nickase Plasmid (h) - sc-414227-NIC from Santa Cruz Biotechnology
|
||||||||
ANKRD13B Double Nickase Plasmid (h2) - sc-414227-NIC-2 from Santa Cruz Biotechnology
|
||||||||
ANKRD13B CRISPR Activation Plasmid (h) - sc-414227-ACT from Santa Cruz Biotechnology
|
||||||||
ANKRD13B CRISPR Activation Plasmid (h2) - sc-414227-ACT-2 from Santa Cruz Biotechnology
|
||||||||
ANKRD13B Lentiviral Activation Particles (h) - sc-414227-LAC from Santa Cruz Biotechnology
|
||||||||
ANKRD13B Lentiviral Activation Particles (h2) - sc-414227-LAC-2 from Santa Cruz Biotechnology
|
||||||||
ANKRD13B siRNA (h) - sc-93649 from Santa Cruz Biotechnology
|
||||||||
ANKRD13B shRNA Plasmid (h) - sc-93649-SH from Santa Cruz Biotechnology
|
||||||||
ANKRD13B shRNA (h) Lentiviral Particles - sc-93649-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU161081 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN3176 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3176 from Sigma-Aldrich
|
||||||||
ANKRD13B siRNA (Human) - CRJ4792 from Cohesion Biosciences
|
||||||||
ANKRD13B - MBS8218730 from MyBioSource
|
||||||||
shRNA set against Human ANKRD13B (NM_152345.4) - SHH236586 from Creative biogene
|
||||||||
shRNA set against Human ANKRD13B(NM_152345.4) - SHG059329 from Creative biogene
|
||||||||
Human ANKRD13B siRNA - orb275293 from Biorbyt
|
||||||||
ANKRD13B shRNA Plasmid (Human) - CHJ4792 from Cohesion Biosciences
|
||||||||
ANKRD13B miRNA 3'UTR clone - MiUTR1H-00381 from Creative biogene
|