Gene Symbol | IL1B |
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Entrez Gene | 768274 |
Alt Symbol | - |
Species | Cat |
Gene Type | protein-coding |
Description | interleukin 1, beta |
Other Description | IL-1 beta|interleukin-1 beta|interleukin-beta |
Swissprots | P41687 |
Accessions | P41687 M92060 AAA30814 NM_001077414 NP_001070882 |
Function | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
Subcellular Location | Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
Top Pathways | Cytosolic DNA-sensing pathway, Apoptosis, NOD-like receptor signaling pathway, Prion diseases, MAPK signaling pathway |
Feline IL1B / Interleukin-1 Beta ELISA Kit - RAB0589 from Sigma-Aldrich
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Feline IL-1 beta ELISA - ELF-IL1b from RayBiotech
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Interleukin-1 beta (IL1B), ELISA Kit - MBS9319075 from MyBioSource
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Feline IL-1B / IL-1 Beta ELISA Kit (Sandwich ELISA) - LS-F3521 from LifeSpan Bioscience
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Cat Interleukin-1 beta (IL1B) ELISA Kit - EKA01179 from Biomatik
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Feline IL-1 beta ELISA - ELF-IL1b-1 from RayBiotech
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