| Gene Symbol |
TESK2
|
| Entrez Gene |
10420
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
testis-specific kinase 2
|
| Other Description |
dual specificity testis-specific protein kinase 2|testicular protein kinase 2
|
| Swissprots |
Q9Y3Q6 Q96S53 Q8N520 Q5T422 Q5T423
|
| Accessions |
CAE91562 EAX06986 EAX06987 EAX06988 EAX06989 Q96S53 AB057597 BAB62909 AJ132545 CAB41970 AK027573 BAG51348 AK294172 BAG57493 AK299269 BAG61291 AK302494 BAG63778 BC022194 BC033085 AAH33085 BX648441 DA990759 DB161528 EU832673 ACE87764 EU832752 ACE87084 XM_005270355 XP_005270412 XM_006710287 XP_006710350 XM_011540497 XP_011538799 XM_011540498 XP_011538800 XM_011540499 XP_011538801 XM_011540500 XP_011538802 NM_007170 NP_009101
|
| Function |
Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:11418599}.
|
| Tissue Specificity |
Predominantly expressed in testis and prostate. Found predominantly in non-germinal Sertoli cells. {ECO:0000269|PubMed:10512679, ECO:0000269|PubMed:11418599}.
|