Gene Symbol | TESK2 |
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Entrez Gene | 10420 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | testis-specific kinase 2 |
Other Description | dual specificity testis-specific protein kinase 2|testicular protein kinase 2 |
Swissprots | Q9Y3Q6 Q96S53 Q8N520 Q5T422 Q5T423 |
Accessions | CAE91562 EAX06986 EAX06987 EAX06988 EAX06989 Q96S53 AB057597 BAB62909 AJ132545 CAB41970 AK027573 BAG51348 AK294172 BAG57493 AK299269 BAG61291 AK302494 BAG63778 BC022194 BC033085 AAH33085 BX648441 DA990759 DB161528 EU832673 ACE87764 EU832752 ACE87084 XM_005270355 XP_005270412 XM_006710287 XP_006710350 XM_011540497 XP_011538799 XM_011540498 XP_011538800 XM_011540499 XP_011538801 XM_011540500 XP_011538802 NM_007170 NP_009101 |
Function | Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11418599}. |
Tissue Specificity | Predominantly expressed in testis and prostate. Found predominantly in non-germinal Sertoli cells. {ECO:0000269|PubMed:10512679, ECO:0000269|PubMed:11418599}. |
TESK2 CRISPR/Cas9 KO Plasmid (h) - sc-411467 from Santa Cruz Biotechnology
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TESK2 HDR Plasmid (h) - sc-411467-HDR from Santa Cruz Biotechnology
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TESK2 Double Nickase Plasmid (h) - sc-411467-NIC from Santa Cruz Biotechnology
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TESK2 Double Nickase Plasmid (h2) - sc-411467-NIC-2 from Santa Cruz Biotechnology
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TESK2 CRISPR Activation Plasmid (h) - sc-411467-ACT from Santa Cruz Biotechnology
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TESK2 CRISPR Activation Plasmid (h2) - sc-411467-ACT-2 from Santa Cruz Biotechnology
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TESK2 Lentiviral Activation Particles (h) - sc-411467-LAC from Santa Cruz Biotechnology
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TESK2 Lentiviral Activation Particles (h2) - sc-411467-LAC-2 from Santa Cruz Biotechnology
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TESK2 siRNA (h) - sc-76644 from Santa Cruz Biotechnology
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TESK2 shRNA Plasmid (h) - sc-76644-SH from Santa Cruz Biotechnology
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TESK2 shRNA (h) Lentiviral Particles - sc-76644-V from Santa Cruz Biotechnology
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TESK2 RNAi - H00010420-R01V from Novus Biologicals
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TESK2 RNAi - H00010420-R03 from Novus Biologicals
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MISSION® esiRNA - EHU062591 from Sigma-Aldrich
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MISSION® siRNA - SIHK2263 from Sigma-Aldrich
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MISSION® siRNA - SIHK2262 from Sigma-Aldrich
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MISSION® siRNA - SIHK2261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21224 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21224 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07398 from Sigma-Aldrich
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TESK2 siRNA (Human) - CRH7065 from Cohesion Biosciences
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TESK2 - MBS8207323 from MyBioSource
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shRNA set against Human TESK2(NM_007170.2) - SHL065566 from Creative biogene
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Human TESK2 siRNA - orb267567 from Biorbyt
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TESK2 shRNA Plasmid (Human) - CHH7065 from Cohesion Biosciences
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