MLC1

Gene Symbol MLC1
Entrez Gene 23209
Alt Symbol LVM, MLC, VL
Species Human
Gene Type protein-coding
Description megalencephalic leukoencephalopathy with subcortical cysts 1
Other Description membrane protein MLC1
Swissprots B7Z659 Q5JZ83 B3KW61 Q96RP5 Q15049 Q9UGY8 Q8TAG4
Accessions EAW73490 EAW73491 Q15049 AF319633 AAK60119 AK124264 BAG54023 AK294048 BAH11657 AK295106 BAH11975 AK297341 BAH12555 AK299841 BAH13145 BC010518 BC028425 AAH28425 BC070042 AAH70042 BF513319 CB155740 CR456460 CAG30346 CU013011 CAK54442 CU013299 CAK54741 D25217 BAA04947 DA212966 XM_011530678 XP_011528980 XR_430476 NM_015166 NP_055981 NM_139202 NP_631941
Function Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx. {ECO:0000269|PubMed:22328087}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell membrane {ECO:0000269|PubMed:22328087}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:22328087}. Endoplasmic reticulum {ECO:0000269|PubMed:22328087}.
Tissue Specificity Expressed in the brain, with highest levels found in the amygdala, nucleus caudatus, thalamus and hippocampus. {ECO:0000269|PubMed:11326298}.

MLC1 CRISPR/Cas9 KO Plasmid (h) - sc-405343 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MLC1 HDR Plasmid (h) - sc-405343-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MLC1 Double Nickase Plasmid (h) - sc-405343-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MLC1 Double Nickase Plasmid (h2) - sc-405343-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MLC1 CRISPR Activation Plasmid (h) - sc-405343-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MLC1 CRISPR Activation Plasmid (h2) - sc-405343-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MLC1 Lentiviral Activation Particles (h) - sc-405343-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MLC1 Lentiviral Activation Particles (h2) - sc-405343-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MLC1 siRNA (h) - sc-75793 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MLC1 shRNA Plasmid (h) - sc-75793-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MLC1 shRNA (h) Lentiviral Particles - sc-75793-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MLC1 RNAi - H00023209-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MLC1 RNAi - H00023209-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU080871 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14390 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14390 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11166 from Sigma-Aldrich

Category miRNA

MLC1 siRNA (Human) - CRH8087 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MLC1 (NM_015166.3) - SHH342404 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MLC1(NM_015166.3) - SHH191585 from Creative biogene

Category siRNA
Species Reactivities Human

MLC1 shRNA Plasmid (Human) - CHH8087 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MLC1 miRNA 3'UTR clone - MiUTR1H-06318 from Creative biogene

Species Reactivities Human
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