MLC1

Gene Symbol MLC1
Entrez Gene 23209
Alt Symbol LVM, MLC, VL
Species Human
Gene Type protein-coding
Description megalencephalic leukoencephalopathy with subcortical cysts 1
Other Description membrane protein MLC1
Swissprots B7Z659 Q5JZ83 B3KW61 Q96RP5 Q15049 Q9UGY8 Q8TAG4
Accessions EAW73490 EAW73491 Q15049 AF319633 AAK60119 AK124264 BAG54023 AK294048 BAH11657 AK295106 BAH11975 AK297341 BAH12555 AK299841 BAH13145 BC010518 BC028425 AAH28425 BC070042 AAH70042 BF513319 CB155740 CR456460 CAG30346 CU013011 CAK54442 CU013299 CAK54741 D25217 BAA04947 DA212966 XM_011530678 XP_011528980 XR_430476 NM_015166 NP_055981 NM_139202 NP_631941
Function Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx. {ECO:0000269|PubMed:22328087}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell membrane {ECO:0000269|PubMed:22328087}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:22328087}. Endoplasmic reticulum {ECO:0000269|PubMed:22328087}.
Tissue Specificity Expressed in the brain, with highest levels found in the amygdala, nucleus caudatus, thalamus and hippocampus. {ECO:0000269|PubMed:11326298}.

MLC1 (C-18) - sc-86740 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
MLC1 (C-18): sc-86740. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic staining of hepatocytes, bile duct cells and hepatic sinusoids.

MLC1 (H-128) - sc-366761 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MLC1 (H-128): sc-366761. Western blot analysis of MLC1 expression in KNRK whole cell lysate.

MLC1 (N-18) - sc-86741 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-MLC1 antibody [EPR10942(2)] - N-terminal - ab186436 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10942(2)
Anti-MLC1 antibody [EPR10942(2)] - N-terminal (ab186436) at 1/10000 dilution + Human hypothalamus lysate at 20 µgSecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-MLC1 antibody - C-terminal - ab139110 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MLC1 antibody - C-terminal (ab139110) at 1/100 dilution + MDA-MB231 cell line lysates at 35 µgdeveloped using the ECL technique

Anti-MLC1 antibody - ab94730 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab94730 staining MLC1 in primary Rat cortical astrocytes by Immunocytochemistry/ Immunofluorescence. Cells were fixed with 4% paraformaldehyde. After 1 hour of incubation with blocking solution (5% BSA in PBS), cells were incubated for 1 hour at room temperature with a NBD phallacidin high-affinity F-actin probe (1/30) to stain actin filaments and visualize the whole cell body, used in combination with ab94730 (1/50) diluted in PBS+0.2% Triton X100.To amplify MLC1 staining, a biotinilated secondary antibody (4.3 µg/ml, Biotin-SP-AffiniPure goat anti-rabbit IgG H+L) followed by incubation with 2 µg/ml streptavidin-TRITC was used.

Anti-MLC / Myosin Light Chain Antibody (phospho-Ser19) - LS-C37419 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MLC / Myosin Light Chain Antibody (clone BGN/0992/6H8) - LS-C55780 from LifeSpan Bioscience

Prices $390.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone BGN/0992/6H8

Anti-MLC / Myosin Light Chain Antibody - LS-C73065 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-MLC / Myosin Light Chain Antibody (phospho-Ser20) - LS-C73067 from LifeSpan Bioscience

Prices $530.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-MLC1 / MLC Antibody (aa337-366, AP) - LS-C263211 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MLC1 / MLC Antibody (aa337-366, APC) - LS-C263212 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MLC1 / MLC Antibody (aa337-366, Azide-free, HRP) - LS-C263215 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MLC1 / MLC Antibody (aa337-366, Biotin) - LS-C263213 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MLC1 / MLC Antibody (aa337-366, FITC) - LS-C263214 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MLC1 / MLC Antibody (aa337-366, PE) - LS-C263216 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MLC1 / MLC Antibody (aa337-366) - LS-C323024 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MLC1 / MLC Antibody (aa179-228) - LS-C110012 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MLC1 / MLC antibody LS-C110012 Western blot of Fetal Spleen lysate.

Anti-MLC1 / MLC Antibody (aa337-366) - LS-C158148 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
MLC1 Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The MLC1 antibody detected the MLC1 protein (arrow).

Anti-MLC1 / MLC Antibody (aa179-193) IHC-plus™ - LS-B10516 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-MLC1 / MLC antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10516 concentration 5 ug/ml.

MLC1 Antibody - NBP1-80073 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MLC1 Antibody [NBP1-80073] - Titration: 0.2-1 ug/ml, Positive Control: Human Spleen.

MLC1 Antibody - NBP2-39086 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MLC1 Antibody [NBP2-39086] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Negative Control.  Lane 3: Overexpression lysate

MLC1 Antibody - NBP1-81555 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: MLC1 Antibody [NBP1-81555] - Staining of human cerebral cortex shows strong nuclear positivity in neuronal cells.

MLC1 Antibody - NBP2-26196 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: MLC1 Antibody [NBP2-26196] - Staining of Hippocampus lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

MLC1 Polyclonal Antibody - bs-7115R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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