| Gene Symbol |
GPSM2
|
| Entrez Gene |
29899
|
| Alt Symbol |
CMCS, DFNB82, LGN, PINS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
G-protein signaling modulator 2
|
| Other Description |
G-protein signalling modulator 2 (AGS3-like, C. elegans)|G-protein-signaling modulator 2|mosaic protein LGN
|
| Swissprots |
Q5T1N8 Q8N0Z5 P81274 Q6IBL7
|
| Accessions |
EAW56340 EAW56341 EAW56342 EAW56343 EAW56344 P81274 AB445462 BAH84760 AI224972 AK295563 BAG58463 AK314249 BAG36915 AY136740 AAN01266 BC027732 AAH27732 CR456786 CAG33067 DC341689 DQ892029 ABM82955 DQ894930 ABM85856 U54999 AAB40385 XM_005270787 XP_005270844 XM_006710589 XP_006710652 XM_011541301 XP_011539603 XM_011541302 XP_011539604 XM_011541303 XP_011539605 NM_013296 NP_037428
|
| Function |
Plays an important role in spindle pole orientation. Interacts and contributes to the functional activity of G(i) alpha proteins. Acts to stabilize the apical complex during neuroblast divisions. {ECO:0000269|PubMed:15632202}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15632202}. Cytoplasm, cell cortex {ECO:0000269|PubMed:15632202}. Note=Localizes in the cytoplasm in the interphase and at cell periphery in the metaphase.
|
| Tissue Specificity |
Ubiquitously expressed.
|
![Western Blot: GPSM2 Overexpression Lysate (Adult Normal) [NBL1-11310] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GPSM2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7845_GPSM2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11310-img0002.jpg)