Gene Symbol | GPSM2 |
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Entrez Gene | 29899 |
Alt Symbol | CMCS, DFNB82, LGN, PINS |
Species | Human |
Gene Type | protein-coding |
Description | G-protein signaling modulator 2 |
Other Description | G-protein signalling modulator 2 (AGS3-like, C. elegans)|G-protein-signaling modulator 2|mosaic protein LGN |
Swissprots | Q5T1N8 Q8N0Z5 P81274 Q6IBL7 |
Accessions | EAW56340 EAW56341 EAW56342 EAW56343 EAW56344 P81274 AB445462 BAH84760 AI224972 AK295563 BAG58463 AK314249 BAG36915 AY136740 AAN01266 BC027732 AAH27732 CR456786 CAG33067 DC341689 DQ892029 ABM82955 DQ894930 ABM85856 U54999 AAB40385 XM_005270787 XP_005270844 XM_006710589 XP_006710652 XM_011541301 XP_011539603 XM_011541302 XP_011539604 XM_011541303 XP_011539605 NM_013296 NP_037428 |
Function | Plays an important role in spindle pole orientation. Interacts and contributes to the functional activity of G(i) alpha proteins. Acts to stabilize the apical complex during neuroblast divisions. {ECO:0000269|PubMed:15632202}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15632202}. Cytoplasm, cell cortex {ECO:0000269|PubMed:15632202}. Note=Localizes in the cytoplasm in the interphase and at cell periphery in the metaphase. |
Tissue Specificity | Ubiquitously expressed. |
LGN CRISPR/Cas9 KO Plasmid (h) - sc-408221 from Santa Cruz Biotechnology
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LGN HDR Plasmid (h) - sc-408221-HDR from Santa Cruz Biotechnology
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LGN Double Nickase Plasmid (h) - sc-408221-NIC from Santa Cruz Biotechnology
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LGN Double Nickase Plasmid (h2) - sc-408221-NIC-2 from Santa Cruz Biotechnology
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LGN CRISPR Activation Plasmid (h) - sc-408221-ACT from Santa Cruz Biotechnology
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LGN CRISPR Activation Plasmid (h2) - sc-408221-ACT-2 from Santa Cruz Biotechnology
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LGN Lentiviral Activation Particles (h) - sc-408221-LAC from Santa Cruz Biotechnology
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LGN Lentiviral Activation Particles (h2) - sc-408221-LAC-2 from Santa Cruz Biotechnology
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LGN siRNA (h) - sc-106999 from Santa Cruz Biotechnology
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LGN shRNA Plasmid (h) - sc-106999-SH from Santa Cruz Biotechnology
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LGN shRNA (h) Lentiviral Particles - sc-106999-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU129221 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9641 from Sigma-Aldrich
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GPSM2 siRNA (Human) - CRH9256 from Cohesion Biosciences
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GPSM2 - MBS8233431 from MyBioSource
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shRNA set against Human GPSM2 (NM_013296.4) - SHH307314 from Creative biogene
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shRNA set against Human GPSM2(NM_013296.4) - SHH102053 from Creative biogene
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Human GPSM2 siRNA - orb269758 from Biorbyt
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GPSM2 shRNA Plasmid (Human) - CHH9256 from Cohesion Biosciences
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GPSM2 miRNA 3'UTR clone - MiUTR3H-10507 from Creative biogene
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