CYP2C19

Gene Symbol	CYP2C19
Entrez Gene	1557
Alt Symbol	CPCJ, CYP2C, CYPIIC17, CYPIIC19, P450C2C, P450IIC19
Species	Human
Gene Type	protein-coding
Description	cytochrome P450, family 2, subfamily C, polypeptide 19
Other Description	(R)-limonene 6-monooxygenase|(S)-limonene 6-monooxygenase|(S)-limonene 7-monooxygenase|S-mephenytoin 4-hydroxylase|cytochrome P-450 II C|cytochrome P450 2C19|cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19|cytochrome P450-11A|cytochrome P450-254C|flavoprotein-linked monooxygenase|mephenytoin 4'-hydroxylase|mephenytoin 4-hydroxylase|microsomal monooxygenase|xenobiotic monooxygenase
Swissprots	Q8WZB1 Q9UCD4 P33259 Q8WZB2 P33261
Accessions	AAL31347 AAL31348 AAV41877 ABZ69068 ABZ69069 ABZ69070 ABZ69071 ABZ69072 ABZ69073 ABZ69074 ABZ69075 ABZ69076 ABZ69077 ABZ69078 ABZ69079 ABZ69080 ABZ69081 ABZ69082 ABZ69083 ABZ69084 ABZ69085 ABZ69086 ABZ69087 ABZ69088 ABZ69089 ABZ69090 ABZ69091 ABZ69092 ABZ69093 ABZ69094 ABZ69095 ABZ69096 ABZ69097 ABZ69098 ABZ69099 ABZ69100 ABZ69101 ABZ69102 ABZ69103 ABZ69104 ABZ69105 ABZ69106 ABZ69107 ABZ69108 ABZ69109 ABZ69110 ABZ69111 ABZ69112 ABZ69113 ABZ69114 ABZ69115 ABZ69116 ABZ69117 ABZ69118 ABZ69119 ABZ69120 ABZ69121 ABZ69122 ABZ69123 ABZ69124 ABZ69125 BAD02827 P33261 BC111846 AAI11847 CB158473 CB161988 M61854 AAB59426 X65962 CAA46778 NM_000769 NP_000760
Function	Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine.
Subcellular Location	Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Top Pathways	Chemical carcinogenesis, Arachidonic acid metabolism, Linoleic acid metabolism, Drug metabolism - cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CYP2C19 ELISA Kit (Cell-Based ELISA) - LS-F3293 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.781-50 ng/ml

Rat CYP2C19 ELISA Kit (Sandwich ELISA) - LS-F9155 from LifeSpan Bioscience Category ELISA Kit Prices $860.00 Sizes 1 plate Sensitivity 0.28 ng/ml Range 0.781-50 ng/ml

Human CYP2C19 ELISA Kit (Sandwich ELISA) - LS-F11194 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.781-50 ng/ml

Cytochrome P450 2C19 (CYP2C19), Human, ELISA Kit - E01C2239 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0ng/ml Range 5.0-100ng/ml

Cytochrome P450 2C19, CYP2C19, Human, ELISA Kit - E5894h from ARP American Research Products Category ELISA Kit Prices $660.00 Sizes 96 t Range 0.156-10 ng/mL

Cytochrome P450 2C19 Colorimetric Cell-Based ELISA - CB6130 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

CYP2C19, ELISA Kit - MBS2516243 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of Rat CYP2C19 is 0.094ng/mL (The sensitivity of this assay, or lowest detectable limit (LDL) was defined as the lowest protein concentration that could be differentiated from zero). Range 0.156-10ng/mL

Cytochrome P450 2C19, ELISA Kit - MBS076362 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.625 ng/ml - 20 ng/ml.

Cytochrome P450 2C19, ELISA Kit - MBS047704 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19, ELISA Kit - MBS072558 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19, ELISA Kit - MBS073861 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19, ELISA Kit - MBS085384 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19, ELISA Kit - MBS074409 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19, ELISA Kit - MBS080829 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19 (CYP2C19), ELISA Kit - MBS7225895 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19 (CYP2C19), ELISA Kit - MBS2020154 from MyBioSource Category ELISA Kit Prices $435.00, $650.00, $895.00, $3,690.00, $6,650.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of CYP2C19 is typically less than 0.28ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.78 -50ng/mL. The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.12ng/mL, 1.56ng/mL, 0.78ng/mL.

Cytochrome P450 2C19 (CYP2C19), ELISA Kit - MBS7221067 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19 (CYP2C19), ELISA Kit - MBS7210341 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19 (CYP2C19), ELISA Kit - MBS7249765 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19 (CYP2C19), ELISA Kit - MBS7209359 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19 (CYP2C19), ELISA Kit - MBS7234984 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19 (CYP2C19), ELISA Kit - MBS7233208 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19 (CYP2C19), ELISA Kit - MBS7224765 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19 (CYP2C19), ELISA Kit - MBS7202244 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome P450 2C19 (CYP2C19), ELISA Kit - MBS7246281 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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