Gene Symbol | SNTA1 |
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Entrez Gene | 6640 |
Alt Symbol | LQT12, SNT1, TACIP1, dJ1187J4.5 |
Species | Human |
Gene Type | protein-coding |
Description | syntrophin, alpha 1 |
Other Description | 59 kDa dystrophin-associated protein A1 acidic component 1|acidic alpha 1 syntrophin|alpha-1-syntrophin|dystrophin-associated protein A1, 59kDa, acidic component|pro-TGF-alpha cytoplasmic domain-interacting protein 1|syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)|syntrophin-1 |
Swissprots | B4DX40 A8K7H9 Q16438 E1P5N1 Q13424 |
Accessions | EAW76314 EAW76315 EAW76316 EAW76317 Q13424 AK095942 BAG53172 AK291994 BAF84683 AK301800 BAG63252 AU118614 BC026215 AAH26215 BC113813 AAI13814 DQ893566 ABM84492 DQ896816 ABM87815 S81737 AAB36398 U40571 AAC50448 XM_005260517 XP_005260574 XM_011529007 XP_011527309 XM_011529008 XP_011527310 XR_936612 NM_003098 NP_003089 |
Function | Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5- bisphosphate (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane, sarcolemma {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell junction {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane and at neuromuscular junctions. {ECO:0000250}. |
Tissue Specificity | High expression in skeletal muscle and heart. Low expression in brain, pancreas, liver, kidney and lung. Not detected in placenta. |
α-Syntrophin (C-16) - sc-13760 from Santa Cruz Biotechnology
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α-Syntrophin (C-7) - sc-166207 from Santa Cruz Biotechnology
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α-Syntrophin (D-7) - sc-166634 from Santa Cruz Biotechnology
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α-Syntrophin (H-65) - sc-50460 from Santa Cruz Biotechnology
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α-Syntrophin (N-19) - sc-13757 from Santa Cruz Biotechnology
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α-Syntrophin (F-1) - sc-166635 from Santa Cruz Biotechnology
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Anti-Syntrophin alpha 1 antibody - ab11187 from Abcam
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Anti-Syntrophin alpha 1 antibody - ab11186 from Abcam
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Anti-Syntrophin alpha 1 antibody - ab5941 from Abcam
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Anti-Syntrophin alpha 1 antibody - ab172204 from Abcam
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Anti-Syntrophin alpha 1 antibody [2E10] - ab118017 from Abcam
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Anti-Syntrophin alpha 1 antibody [EPR14828] - ab188873 from Abcam
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Anti-Syntrophin antibody [1351] - ab11425 from Abcam
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Anti-SNTA1 / Syntrophin Alpha 1 Antibody (Cytoplasmic Domain) - LS-C89922 from LifeSpan Bioscience
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Anti-SNTA1 / Syntrophin Alpha 1 Antibody (Cytoplasmic Domain) - LS-C89921 from LifeSpan Bioscience
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Anti-SNTA1 / Syntrophin Alpha 1 Antibody (clone 2E10) - LS-C115815 from LifeSpan Bioscience
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Anti-SNTA1 / Syntrophin Alpha 1 Antibody (clone 1D4) - LS-C115819 from LifeSpan Bioscience
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Anti-SNTA1 / Syntrophin Alpha 1 Antibody (aa92-141) - LS-C187350 from LifeSpan Bioscience
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Anti-SNTA1 / Syntrophin Alpha 1 Antibody (clone 2A2) - LS-C115821 from LifeSpan Bioscience
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Anti-SNTA1 / Syntrophin Alpha 1 Antibody (aa2-14) - LS-C20218 from LifeSpan Bioscience
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Anti-SNTA1 / Syntrophin Alpha 1 Antibody (clone AT1E1) - LS-C200837 from LifeSpan Bioscience
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Anti-SNTA1 / Syntrophin Alpha 1 Antibody (clone 2D5) - LS-C337159 from LifeSpan Bioscience
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Anti-SNTA1 / Syntrophin Alpha 1 Antibody (clone 1C7) - LS-C115822 from LifeSpan Bioscience
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Anti-SNTA1 / Syntrophin Alpha 1 Antibody (clone 2B4) - LS-C337160 from LifeSpan Bioscience
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Anti-SNTA1 / Syntrophin Alpha 1 Antibody (aa191-505) IHC-plus⢠- LS-B10903 from LifeSpan Bioscience
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