| Gene Symbol |
LTB
|
| Entrez Gene |
4050
|
| Alt Symbol |
TNFC, TNFSF3, p33
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
lymphotoxin beta (TNF superfamily, member 3)
|
| Other Description |
LT-beta|TNF-C|lymphotoxin-beta|tumor necrosis factor C|tumor necrosis factor ligand superfamily member 3
|
| Swissprots |
Q52LU8 P78370 Q06643 Q99761
|
| Accessions |
AAA99888 AAD18089 AAL49954 AAL49955 AAO21134 BAB63395 BAC54938 BAE78640 BAF31273 CAA75069 CAI95950 EAX03425 EAX03426 Q06643 AK312210 BAG35143 BC055090 BC055094 BC069330 AAH69330 BC093783 AAH93783 L11015 AAA36191 U79029 AAB37342 U89922 AAC51769 NM_002341 NP_002332 NM_009588 NP_033666
|
| Function |
Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Spleen and thymus.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Rheumatoid arthritis
|