Gene Symbol |
ATP12A
|
Entrez Gene |
479
|
Alt Symbol |
ATP1AL1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
|
Other Description |
ATPase, Na+/K+ transporting, alpha polypeptide-like 1|non-gastric H(+)/K(+) ATPase alpha subunit|non-gastric H(+)/K(+) ATPase subunit alpha|potassium-transporting ATPase alpha chain 2|proton pump
|
Swissprots |
P54707 Q13816 Q8N5U2 Q5W035 Q16734 Q13817
|
Accessions |
AAA35576 AAC37589 CAA49477 CAA49478 EAX08343 EAX08344 EAX08345 EAX08346 P54707 AK292968 BAF85657 AK303498 BAG64531 BC031609 AAH31609 CA450333 DB216724 DB232979 JF432299 ADZ15516 M16797 AAA51802 U02076 AAB37755 NM_001185085 NP_001172014 NM_001676 NP_001667
|
Function |
Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Found in skin and kidney. Detected in prostate basal cells (at protein level). Expression is increased in benign prostate hyperplasia and tumor tissues (at protein level). {ECO:0000269|PubMed:22179016, ECO:0000269|PubMed:9872395}.
|
Top Pathways |
Oxidative phosphorylation
|