| Gene Symbol |
HEPH
|
| Entrez Gene |
9843
|
| Alt Symbol |
CPL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
hephaestin
|
| Other Description |
-
|
| Swissprots |
Q9BQS7 Q9C058 E9PHN8 Q6UW45 B1AJX8 O75180 D3DVT7
|
| Accessions |
ABF47089 EAX05384 EAX05385 EAX05386 EAX05387 EAX05388 Q9BQS7 AB014598 BAA31673 AF075034 AF148860 AAK08131 AJ296162 CAC35365 AK022472 AK294278 BAG57564 AK295456 BAG58390 AK307761 AK311043 AK316231 BAH14602 AY358990 AAQ89349 BC011561 AAH11561 BP282214 CN361718 DQ893628 ABM84554 EU176678 ABW03479 EU831491 ACE87178 EU831578 ACE86497 XM_006724722 XP_006724785 XM_011531073 XP_011529375 XM_011531074 XP_011529376 XM_011531075 XP_011529377 NM_001130860 NP_001124332 NM_001282141 NP_001269070 NM_014799 NP_055614 NM_138737 NP_620074
|
| Function |
May function as a ferroxidase for ferrous (II) to ferric ion (III) conversion and may be involved in copper transport and homeostasis. Implicated in iron homeostasis and may mediate iron efflux associated to ferroportin 1.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Detected in breast, colon, bone trabecular cells and fibroblasts.
|
| Top Pathways |
Mineral absorption, Porphyrin and chlorophyll metabolism
|