Gene Symbol | HEPH |
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Entrez Gene | 9843 |
Alt Symbol | CPL |
Species | Human |
Gene Type | protein-coding |
Description | hephaestin |
Other Description | - |
Swissprots | Q9BQS7 Q9C058 E9PHN8 Q6UW45 B1AJX8 O75180 D3DVT7 |
Accessions | ABF47089 EAX05384 EAX05385 EAX05386 EAX05387 EAX05388 Q9BQS7 AB014598 BAA31673 AF075034 AF148860 AAK08131 AJ296162 CAC35365 AK022472 AK294278 BAG57564 AK295456 BAG58390 AK307761 AK311043 AK316231 BAH14602 AY358990 AAQ89349 BC011561 AAH11561 BP282214 CN361718 DQ893628 ABM84554 EU176678 ABW03479 EU831491 ACE87178 EU831578 ACE86497 XM_006724722 XP_006724785 XM_011531073 XP_011529375 XM_011531074 XP_011529376 XM_011531075 XP_011529377 NM_001130860 NP_001124332 NM_001282141 NP_001269070 NM_014799 NP_055614 NM_138737 NP_620074 |
Function | May function as a ferroxidase for ferrous (II) to ferric ion (III) conversion and may be involved in copper transport and homeostasis. Implicated in iron homeostasis and may mediate iron efflux associated to ferroportin 1. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Detected in breast, colon, bone trabecular cells and fibroblasts. |
Top Pathways | Mineral absorption, Porphyrin and chlorophyll metabolism |
Hephaestin (C-7) - sc-365365 from Santa Cruz Biotechnology
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Hephaestin (H-90) - sc-134444 from Santa Cruz Biotechnology
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Hephaestin (N-20) - sc-49970 from Santa Cruz Biotechnology
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Hephaestin (L-20) - sc-49969 from Santa Cruz Biotechnology
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Anti-Hephaestin antibody - ab56729 from Abcam
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Anti-Hephaestin antibody - ab95137 from Abcam
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Anti-Hephaestin antibody - ab183647 from Abcam
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Anti-Hephaestin antibody - Carboxyterminal end - ab56042 from Abcam
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Anti-HEPH / Hephaestin Antibody (C-Terminus) - LS-C24201 from LifeSpan Bioscience
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Anti-HEPH / Hephaestin Antibody (C-Terminus) - LS-C24202 from LifeSpan Bioscience
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Anti-HEPH / Hephaestin Antibody (C-Terminus) - LS-C46899 from LifeSpan Bioscience
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Anti-HEPH / Hephaestin Antibody (C-Terminus) - LS-C46917 from LifeSpan Bioscience
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Anti-HEPH / Hephaestin Antibody (aa315-425, clone 10D112, Azide-free) - LS-C183684 from LifeSpan Bioscience
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Anti-HEPH / Hephaestin Antibody (aa315-424) - LS-C308213 from LifeSpan Bioscience
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Anti-HEPH / Hephaestin Antibody (N-Terminus) - LS-C80989 from LifeSpan Bioscience
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Hephaestin Antibody - NBP1-85483 from Novus Biologicals
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Hephaestin Antibody - NBP1-62496 from Novus Biologicals
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Hephaestin Antibody - H00009843-A01 from Novus Biologicals
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Hephaestin Antibody (2D3) - H00009843-M01 from Novus Biologicals
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Hephaestin Polyclonal Antibody - bs-15458R from Bioss
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Monoclonal Anti-HEPH antibody produced in mouse - WH0009843M1 from Sigma-Aldrich
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Anti-HEPH antibody produced in rabbit - SAB2101029 from Sigma-Aldrich
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HEPH antibody - N-terminal region (ARP47078_P050) - ARP47078_P050 from Aviva Systems Biology
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HEPH-Antibody-monoclonal-M01 - AT2350a from Abgent, a WuXi AppTec company
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Hephaestin antibody [C2C3], C-term - GTX115299 from GeneTex
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