| Gene Symbol |
ANAPC16
|
| Entrez Gene |
119504
|
| Alt Symbol |
APC16, C10orf104, CENP-27, MSAG, bA570G20.3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
anaphase promoting complex subunit 16
|
| Other Description |
anaphase-promoting complex subunit 16|centromere protein 27|cyclosome subunit 16|metabolic syndrome-associated protein
|
| Swissprots |
Q96DE5
|
| Accessions |
EAW54448 EAW54449 EAW54450 EAW54451 Q96DE5 AI038150 AK023981 BC009530 AAH09530 BF975718 BM768948 CB984695 CD511334 CD724246 DA310509 DA739927 EU552924 ACD68153 NM_001242546 NP_001229475 NM_001242547 NP_001229476 NM_001242548 NP_001229477 NM_173473 NP_775744 NR_038391 NR_038392
|
| Function |
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:20360068}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:20360068}. Nucleus {ECO:0000269|PubMed:20360068}.
|
![Western Blot: ANAPC16 Overexpression Lysate (Adult Normal) [NBL1-08068] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ANAPC16.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/7922_ANAPC16%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-08068-img0002.jpg)