Gene Symbol | ANAPC16 |
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Entrez Gene | 119504 |
Alt Symbol | APC16, C10orf104, CENP-27, MSAG, bA570G20.3 |
Species | Human |
Gene Type | protein-coding |
Description | anaphase promoting complex subunit 16 |
Other Description | anaphase-promoting complex subunit 16|centromere protein 27|cyclosome subunit 16|metabolic syndrome-associated protein |
Swissprots | Q96DE5 |
Accessions | EAW54448 EAW54449 EAW54450 EAW54451 Q96DE5 AI038150 AK023981 BC009530 AAH09530 BF975718 BM768948 CB984695 CD511334 CD724246 DA310509 DA739927 EU552924 ACD68153 NM_001242546 NP_001229475 NM_001242547 NP_001229476 NM_001242548 NP_001229477 NM_173473 NP_775744 NR_038391 NR_038392 |
Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:20360068}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20360068}. Nucleus {ECO:0000269|PubMed:20360068}. |
APC16 CRISPR/Cas9 KO Plasmid (h) - sc-417911 from Santa Cruz Biotechnology
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APC16 HDR Plasmid (h) - sc-417911-HDR from Santa Cruz Biotechnology
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APC16 Double Nickase Plasmid (h) - sc-417911-NIC from Santa Cruz Biotechnology
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APC16 Double Nickase Plasmid (h2) - sc-417911-NIC-2 from Santa Cruz Biotechnology
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APC16 CRISPR Activation Plasmid (h) - sc-417911-ACT from Santa Cruz Biotechnology
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APC16 CRISPR Activation Plasmid (h2) - sc-417911-ACT-2 from Santa Cruz Biotechnology
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APC16 Lentiviral Activation Particles (h) - sc-417911-LAC from Santa Cruz Biotechnology
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APC16 Lentiviral Activation Particles (h2) - sc-417911-LAC-2 from Santa Cruz Biotechnology
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APC16 siRNA (h) - sc-90685 from Santa Cruz Biotechnology
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APC16 shRNA Plasmid (h) - sc-90685-SH from Santa Cruz Biotechnology
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APC16 shRNA (h) Lentiviral Particles - sc-90685-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU011861 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3139 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11705 from Sigma-Aldrich
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ANAPC16 siRNA (Human) - CRJ4613 from Cohesion Biosciences
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ANAPC16 - MBS8213525 from MyBioSource
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CompoZr ® Knockout ZFN Kit - CKOZFN3139 from Sigma-Aldrich
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shRNA set against Human ANAPC16 (NM_173473.3) - SHH236110 from Creative biogene
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ANAPC16 shRNA Plasmid (Human) - CHJ4613 from Cohesion Biosciences
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ANAPC16 miRNA 3'UTR clone - MiUTR4H-TG10558 from Creative biogene
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