Gene Symbol | ENPP3 |
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Entrez Gene | 5169 |
Alt Symbol | B10, CD203c, NPP3, PD-IBETA, PDNP3 |
Species | Human |
Gene Type | protein-coding |
Description | ectonucleotide pyrophosphatase/phosphodiesterase 3 |
Other Description | dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3)|dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3)|ectonucleotide pyrophosphatase/phosphodiesterase family member 3|gp130RB13-6|phosphodiesterase I/nucleotide pyrophosphatase 3|phosphodiesterase-I beta |
Swissprots | O14638 Q5JTL3 |
Accessions | AAD05192 AAD46160 CAB99214 CCA64000 CDH92907 EAW48044 EAW48045 EAW48046 O14638 AK024899 AK226107 AK292903 BAF85592 AK296080 BAG58836 AK309080 AK310691 AK315893 BAF98784 BC141434 AAI41435 BC146579 AAI46580 DB230886 DB239180 DQ234347 ABB29976 EF560735 ABQ59045 XM_011535897 XP_011534199 XR_245539 NM_005021 NP_005012 |
Function | Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD. {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Secreted {ECO:0000269|PubMed:11342463, ECO:0000269|PubMed:15072822}. Note=Located to the apical surface in intestinal and kidney epithelial cells. Located to the cell surface of basophils, and to the apical plasma membrane of bile duct cells. Secreted in serum, and in lumen of epithelial cells. |
Tissue Specificity | Expressed in bile ducts, prostate, uterus and colon. Exclusively expressed on basophils, mast cells and their progenitors. {ECO:0000269|PubMed:15072822, ECO:0000269|PubMed:9344668}. |
Top Pathways | Purine metabolism, Nicotinate and nicotinamide metabolism, Riboflavin metabolism, Pantothenate and CoA biosynthesis, Starch and sucrose metabolism |
Human ENPP3 protein fragment - ab159085 from Abcam
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ENPP3 / CD203c Antibody Blocking Peptide - LS-E29778 from LifeSpan Bioscience
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ENPP3 / CD203c Antibody Blocking Peptide - LS-E29779 from LifeSpan Bioscience
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ENPP3 / CD203c Antibody Blocking Peptide - LS-E29570 from LifeSpan Bioscience
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ENPP3 / CD203c Antibody Blocking Peptide - LS-E29571 from LifeSpan Bioscience
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Recombinant Human ENPP-3/CD203c Protein - H00005169-Q01 from Novus Biologicals
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Cynomolgus CD203c protein - orb138757 from Biorbyt
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CD203c Blocking Peptide - abx063063 from Abbexa
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CD203c / ENPP3 - H00005169-Q01-10 from Acris Antibodies
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CD203c / ENPP3 - H00005169-Q01-25 from Acris Antibodies
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ENPP3 fusion protein - ag18892 from Proteintech Group
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ENPP3 fusion protein - ag18813 from Proteintech Group
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CD203c Blocking Peptide - CBP1869 from Cohesion Biosciences
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ENPP3 Peptide - BS60438P from Bioworld Technology
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Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 3(ENPP3) ,partial - CSB-YP007681HU CSB-EP007681HU CSB-BP007681HU CSB-MP007681HU from Cusabio
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CD203c / ENPP3 - TP324818 from Acris Antibodies
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ENPP-3/CD203c Protein - NBP1-88928PEP from Novus Biologicals
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CD203c Blocking Peptide - abx162109 from Abbexa
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ENPP3-Blocking-PeptideC-term - BP19749b from Abgent, a WuXi AppTec company
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ENPP3 Peptide, Human - M34GP04948H from Creative Peptides
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CD203c Blocking Peptide - CBP4898 from Cohesion Biosciences
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Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (ENPP3), partial, Recombinant Protein - MBS1145641 from MyBioSource
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ENPP3 peptide - orb72646 from Biorbyt
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CD203c peptide - orb316042 from Biorbyt
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Recombinant Human ENPP3 Protein, Myc/DDK-tagged - ENPP3-3324H from Creative Biomart
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