ENPP3

Gene Symbol	ENPP3
Entrez Gene	5169
Alt Symbol	B10, CD203c, NPP3, PD-IBETA, PDNP3
Species	Human
Gene Type	protein-coding
Description	ectonucleotide pyrophosphatase/phosphodiesterase 3
Other Description	dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3)|dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3)|ectonucleotide pyrophosphatase/phosphodiesterase family member 3|gp130RB13-6|phosphodiesterase I/nucleotide pyrophosphatase 3|phosphodiesterase-I beta
Swissprots	O14638 Q5JTL3
Accessions	AAD05192 AAD46160 CAB99214 CCA64000 CDH92907 EAW48044 EAW48045 EAW48046 O14638 AK024899 AK226107 AK292903 BAF85592 AK296080 BAG58836 AK309080 AK310691 AK315893 BAF98784 BC141434 AAI41435 BC146579 AAI46580 DB230886 DB239180 DQ234347 ABB29976 EF560735 ABQ59045 XM_011535897 XP_011534199 XR_245539 NM_005021 NP_005012
Function	Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD. {ECO:0000250}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Secreted {ECO:0000269|PubMed:11342463, ECO:0000269|PubMed:15072822}. Note=Located to the apical surface in intestinal and kidney epithelial cells. Located to the cell surface of basophils, and to the apical plasma membrane of bile duct cells. Secreted in serum, and in lumen of epithelial cells.
Tissue Specificity	Expressed in bile ducts, prostate, uterus and colon. Exclusively expressed on basophils, mast cells and their progenitors. {ECO:0000269|PubMed:15072822, ECO:0000269|PubMed:9344668}.
Top Pathways	Purine metabolism, Nicotinate and nicotinamide metabolism, Riboflavin metabolism, Pantothenate and CoA biosynthesis, Starch and sucrose metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

CD203c CRISPR/Cas9 KO Plasmid (h) - sc-404517 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CD203c HDR Plasmid (h) - sc-404517-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CD203c Double Nickase Plasmid (h) - sc-404517-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CD203c Double Nickase Plasmid (h2) - sc-404517-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CD203c CRISPR Activation Plasmid (h) - sc-404517-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CD203c CRISPR Activation Plasmid (h2) - sc-404517-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CD203c Lentiviral Activation Particles (h) - sc-404517-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CD203c Lentiviral Activation Particles (h2) - sc-404517-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CD203c siRNA (h) - sc-106764 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CD203c shRNA Plasmid (h) - sc-106764-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CD203c shRNA (h) Lentiviral Particles - sc-106764-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ENPP-3/CD203c RNAi - H00005169-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU086531 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0167 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0168 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0166 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN7882 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7882 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05146 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr05146

ENPP3 siRNA (Human) - CRH3449 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ENPP3 - MBS8232308 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ENPP3(NM_005021.3) - SHH034121 from Creative biogene Category siRNA Species Reactivities Human

Human ENPP3 siRNA - orb263951 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ENPP3 shRNA Plasmid (Human) - CHH3449 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ENPP3 miRNA 3'UTR clone - MiUTR1H-03230 from Creative biogene Species Reactivities Human

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