| Gene Symbol |
STAB1
|
| Entrez Gene |
23166
|
| Alt Symbol |
CLEVER-1, FEEL-1, FELE-1, FEX1, STAB-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
stabilin 1
|
| Other Description |
MS-1 antigen|common lymphatic endothelial and vascular endothelial receptor-1|fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger receptor-1|fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1|stabilin-1
|
| Swissprots |
A7E297 Q9NY15 Q8IUH1 Q93072 Q8IUH0
|
| Accessions |
EAW65232 EAW65233 EAW65234 Q9NY15 AB052956 BAC15606 AB052957 BAC15607 AJ275213 CAB61827 AK091600 AK093774 BAG52762 AK097061 AK310105 BC150250 AAI50251 BE242606 BI001474 D87433 BAA13377 DQ786774 ABG91068 HQ013242 XM_005264973 XP_005265030 XM_005264974 XP_005265031 XM_005264975 XP_005265032 XM_006713065 XP_006713128 XM_011533528 XP_011531830 XR_940395 NM_015136 NP_055951
|
| Function |
Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system. {ECO:0000269|PubMed:12077138, ECO:0000269|PubMed:16357325}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
| Tissue Specificity |
High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells. {ECO:0000269|PubMed:11829752, ECO:0000269|PubMed:12077138}.
|