| Gene Symbol | STAB1 |
|---|---|
| Entrez Gene | 23166 |
| Alt Symbol | CLEVER-1, FEEL-1, FELE-1, FEX1, STAB-1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | stabilin 1 |
| Other Description | MS-1 antigen|common lymphatic endothelial and vascular endothelial receptor-1|fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger receptor-1|fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1|stabilin-1 |
| Swissprots | A7E297 Q9NY15 Q8IUH1 Q93072 Q8IUH0 |
| Accessions | EAW65232 EAW65233 EAW65234 Q9NY15 AB052956 BAC15606 AB052957 BAC15607 AJ275213 CAB61827 AK091600 AK093774 BAG52762 AK097061 AK310105 BC150250 AAI50251 BE242606 BI001474 D87433 BAA13377 DQ786774 ABG91068 HQ013242 XM_005264973 XP_005265030 XM_005264974 XP_005265031 XM_005264975 XP_005265032 XM_006713065 XP_006713128 XM_011533528 XP_011531830 XR_940395 NM_015136 NP_055951 |
| Function | Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system. {ECO:0000269|PubMed:12077138, ECO:0000269|PubMed:16357325}. |
| Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Tissue Specificity | High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells. {ECO:0000269|PubMed:11829752, ECO:0000269|PubMed:12077138}. |
Stabilin-1 CRISPR/Cas9 KO Plasmid (h) - sc-406773 from Santa Cruz Biotechnology
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Stabilin-1 HDR Plasmid (h) - sc-406773-HDR from Santa Cruz Biotechnology
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Stabilin-1 Double Nickase Plasmid (h) - sc-406773-NIC from Santa Cruz Biotechnology
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Stabilin-1 Double Nickase Plasmid (h2) - sc-406773-NIC-2 from Santa Cruz Biotechnology
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Stabilin-1 CRISPR Activation Plasmid (h) - sc-406773-ACT from Santa Cruz Biotechnology
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Stabilin-1 CRISPR Activation Plasmid (h2) - sc-406773-ACT-2 from Santa Cruz Biotechnology
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Stabilin-1 Lentiviral Activation Particles (h) - sc-406773-LAC from Santa Cruz Biotechnology
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Stabilin-1 Lentiviral Activation Particles (h2) - sc-406773-LAC-2 from Santa Cruz Biotechnology
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Stabilin-1 siRNA (h) - sc-45784 from Santa Cruz Biotechnology
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Stabilin-1 shRNA Plasmid (h) - sc-45784-SH from Santa Cruz Biotechnology
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Stabilin-1 shRNA (h) Lentiviral Particles - sc-45784-V from Santa Cruz Biotechnology
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Stabilin-1 RNAi - H00023166-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN20680 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20680 from Sigma-Aldrich
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STAB1 siRNA (Human) - CRH8049 from Cohesion Biosciences
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STAB1 - MBS8239660 from MyBioSource
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Stabilin-1 CRISPR/Cas9 KO Plasmid (h2) - sc-406773-KO-2 from Santa Cruz Biotechnology
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Stabilin-1 HDR Plasmid (h2) - sc-406773-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human STAB1 (NM_015136.2) - SHH419076 from Creative biogene
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shRNA set against Human STAB1(NM_015136.2) - SHL039222 from Creative biogene
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Human STAB1 siRNA - orb268551 from Biorbyt
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STAB1 shRNA Plasmid (Human) - CHH8049 from Cohesion Biosciences
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STAB1 miRNA 3'UTR clone - MiUTR1H-09964 from Creative biogene
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