| Gene Symbol |
MYOD1
|
| Entrez Gene |
4654
|
| Alt Symbol |
MYF3, MYOD, PUM, bHLHc1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
myogenic differentiation 1
|
| Other Description |
class C basic helix-loop-helix protein 1|myf-3|myoblast determination protein 1|myogenic factor 3
|
| Swissprots |
O75321 P15172
|
| Accessions |
AAC29001 EAW68427 P15172 AI300241 AK314968 BAG37469 BC064493 AAH64493 BF205042 BF304059 BT007157 AAP35821 X17650 CAA35640 X56677 CAA40000 NM_002478 NP_002469
|
| Function |
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus.
|
![Western Blot: MyoD1 Overexpression Lysate (Adult Normal) [NBL1-13443] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MyoD1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/784_MyoD1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13443-img0002.jpg)