Gene Symbol | MYOD1 |
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Entrez Gene | 4654 |
Alt Symbol | MYF3, MYOD, PUM, bHLHc1 |
Species | Human |
Gene Type | protein-coding |
Description | myogenic differentiation 1 |
Other Description | class C basic helix-loop-helix protein 1|myf-3|myoblast determination protein 1|myogenic factor 3 |
Swissprots | O75321 P15172 |
Accessions | AAC29001 EAW68427 P15172 AI300241 AK314968 BAG37469 BC064493 AAH64493 BF205042 BF304059 BT007157 AAP35821 X17650 CAA35640 X56677 CAA40000 NM_002478 NP_002469 |
Function | Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. |
MyoD CRISPR/Cas9 KO Plasmid (h) - sc-400092 from Santa Cruz Biotechnology
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MyoD HDR Plasmid (h) - sc-400092-HDR from Santa Cruz Biotechnology
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MyoD Double Nickase Plasmid (h) - sc-400092-NIC from Santa Cruz Biotechnology
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MyoD Double Nickase Plasmid (h2) - sc-400092-NIC-2 from Santa Cruz Biotechnology
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MyoD CRISPR Activation Plasmid (h) - sc-400092-ACT from Santa Cruz Biotechnology
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MyoD CRISPR Activation Plasmid (h2) - sc-400092-ACT-2 from Santa Cruz Biotechnology
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MyoD Lentiviral Activation Particles (h) - sc-400092-LAC from Santa Cruz Biotechnology
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MyoD Lentiviral Activation Particles (h2) - sc-400092-LAC-2 from Santa Cruz Biotechnology
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MyoD siRNA (h) - sc-35990 from Santa Cruz Biotechnology
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MyoD shRNA Plasmid (h) - sc-35990-SH from Santa Cruz Biotechnology
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MyoD shRNA (h) Lentiviral Particles - sc-35990-V from Santa Cruz Biotechnology
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MyoD RNAi - H00004654-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN14871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14871 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04813 from Sigma-Aldrich
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MYOD1 siRNA (Human) - CRH3077 from Cohesion Biosciences
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shRNA set against Human MYOD1 (NM_002478.4) - SHH348380 from Creative biogene
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shRNA set against Human MYOD1(NM_002478.4) - SHH213617 from Creative biogene
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MYOD1 shRNA Plasmid (Human) - CHH3077 from Cohesion Biosciences
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MYOD1 miRNA 3'UTR clone - MiUTR1H-06604 from Creative biogene
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